Table 3 Distribution of cases and controls among the high or low level categories of the hemostatic parameters
Hemostatic parameter | Cases (n) | Controls (n) | OR | 95% CI | P-value |
|---|---|---|---|---|---|
Coagulation activity: | |||||
ETP (%)* | |||||
<90th percentile | 309 | 246 | Ref. | Ref. | Ref. |
>90th percentile | 37 | 27 | 1.09 | 0.65-1.84 | 0.744 |
Lag time (%)* | |||||
>10th percentile | 211 | 246 | Ref. | Ref. | Ref. |
<10th percentile | 135 | 27 | 5.83 | 3.71-9.16 | <0.001 |
ttPeak (%)* | |||||
>10th percentile | 206 | 249 | Ref. | Ref. | Ref. |
<10th percentile | 140 | 24 | 7.05 | 4.40-11.29 | <0.001 |
Peak (%)* | |||||
<90th percentile | 208 | 246 | Ref. | Ref. | Ref. |
>90thpercentile | 138 | 27 | 6.05 | 3.85-9.50 | <0.001 |
APC resistance (nAPC-sr) | |||||
FV Leiden non-carriers | |||||
<90th percentile | 190 | 228 | Ref. | Ref. | Ref. |
>90th percentile | 135 | 25 | 6.48 | 4.06-10.35 | <0.001 |
FV Leiden carriers | |||||
<90th percentile | 4 | 18 | Ref. | Ref. | Ref. |
>90th percentile | 17 | 2 | 38.3 | 6.2-236.6 | <0.001 |
D-dimer (ng/mL) | |||||
<90th percentile | 292 | 246 | Ref. | Ref. | Ref. |
>90th percentile | 65 | 27 | 2.03 | 1.26-3.28 | 0.004 |
Coagulation inhibitors: | |||||
AT (%) | |||||
>10th percentile | 215 | 246 | Ref. | Ref. | Ref. |
<10th percentile | 135 | 27 | 5.72 | 3.64-8.99 | <0.001 |
Protein C (%) | |||||
>10th percentile | 310 | 246 | Ref. | Ref. | Ref. |
<10th percentile | 40 | 27 | 1.18 | 0.702-1.97 | 0.539 |
Protein S (%) | |||||
>10th percentile | 325 | 246 | Ref. | Ref. | Ref. |
<10th percentile | 22 | 27 | 0.62 | 0.34-1.11 | 0.106 |
Free TFPI (ng/mL) | |||||
>10th percentile | 319 | 246 | Ref. | Ref. | Ref. |
<10th percentile | 39 | 27 | 1.11 | 0.66-1.87 | 0.683 |