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Table 1 EET-related gene expression in noncancerous tissue and adjacent breast cancer tissue

From: Elevated 14,15- epoxyeicosatrienoic acid by increasing of cytochrome P450 2C8, 2C9 and 2J2 and decreasing of soluble epoxide hydrolase associated with aggressiveness of human breast cancer

EET-related genes Non-cancerous tissue Breast cancer tissue, no. of samples (%) P value*
- + ++
CYP2C8 - 28 (70%) 4 (10%) 4 (10%) 0.019
  + 0 0 2 (5%)
  ++ 0 0 2 (5%)
CYP2C9 - 12 (30%) 6 (15%) 4 (10%) 0.094
  + 4 (10%) 2 (5%) 6 (15%)
  ++ 0 2 (5%) 4 (10%)
CYP2J2 - 28 (70%) 6 (15%) 2 (5%) 0.019
  + 0 0 2 (5%)
  ++ 0 0 2 (5%)
sEH - 10 (25%) 6 (15%) 0 0.034
  + 6 (15%) 2 (5%) 4 (10%)
  ++ 8 (20%) 2 (5%) 2 (5%)
  1. Sum of frequency and intensity scores: 0 or 1, negative (−); 2 or 3, moderately positive (+); 4 to 6, highly positive (++).
  2. *Spearman correlation was used to analyze the correlation of clinicopathological variables and EET-related genes expression.
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