Table 2 MiRNA signature associated with biologically high-grade MCTs

Upregulated miRNAs

hsa-miR-301b

4.2

0.00022

hsa-miR-520b

1.8

1.8

hsa-miR-454

2.4

0.00032

hsa-miR-216b

4.6

0.023

hsa-miR-9

3.2

0.0010

hsa-miR-302b

3.2

0.024

hsa-miR-147

3.9

0.0017

hsa-miR-106b

1.6

0.026

hsa-miR-138

2.5

0.0022

hsa-miR-618

3.0

0.027

hsa-miR-330-5p

3.1

0.0027

hsa-miR-518f

3.2

0.029

hsa-miR-187

5.1

0.0029

hsa-miR-182

2.8

0.030

hsa-miR-106a

2.1

0.0044

hsa-miR-142-5p

1.7

0.031

hsa-miR-636

2.7

0.0052

hsa-miR-301a

2.8

0.032

hsa-miR-17

2.0

0.0057

hsa-miR-217

3.9

0.033

hsa-miR-449b

3.2

0.0069

hsa-miR-652

2.0

0.039

hsa-miR-130b

2.2

0.0082

hsa-miR-186

1.5

0.039

hsa-miR-192

2.5

0.0095

hsa-miR-19a

1.8

0.040

hsa-miR-448

3.1

0.010

hsa-miR-872

1.5

0.041

hsa-miR-425

3.0

0.011

hsa-miR-148b

1.8

0.043

hsa-miR-193a-3p

2.6

0.011

hsa-miR-451

2.4

0.044

hsa-miR-18b

2.2

0.014

hsa-miR-423-5p

1.7

0.048

hsa-miR-93

2.1

0.014

hsa-miR-191

1.5

0.049

hsa-miR-548b-5p

2.3

0.015

Downregulated miRNAs

hsa-miR-25

2.1

0.015

hsa-miR-885-5p

-4.2

0.00011

hsa-miR-324-3p

2.3

0.017

hsa-miR-874

-5.8

0.00018

hsa-miR-326

2.6

0.017

hsa-miR-486-3p

-4.6

0.00040

hsa-miR-18a

3.1

0.017

hsa-miR-299-5p

-4.2

0.0020

hsa-miR-20b

2.0

0.017

hsa-miR-488

-3.9

0.0063

hsa-miR-194

2.8

0.019

hsa-miR-200a

-5.5

0.034

hsa-miR-372

2.4

0.019

hsa-miR-412

-2.8

0.035