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Table 1 Candidate biomarkers

From: MEK1 is associated with carboplatin resistance and is a prognostic biomarker in epithelial ovarian cancer

Gene

Platinum-treated patients (n = 1,152)

siRNA

Affy ID

Gene

ROC (AUC)

ROC (p value)

siRNA ID

214692_s_at

JRK

0.62

1.34*10-7

-

200910_at

CCT3

0.62

3.50*10-7

s14397

212301_at

RTF1

0.62

5.87*10-7

s23185

202670_at

MEK1

0.61

1.75*10-6

s1167

214094_at

FUBP1

0.61

2.25*10-6

s16966

202162_s_at

CNOT8

0.61

3.07*10-6

s17848

217527_s_at

NFATC2IP

0.61

3.69*10-6

s39617

202646_s_at

CSDE1

0.6

4.18*10-6

s15374

214093_s_at

FUBP1

0.61

5.34*10-6

s16966

  1. The eight strongest genes selected for in vitro validation including the results of the bioinformatic processing performed using transcriptomic data of 1,145 platinum-treated ovarian cancer patients.