An increased risk of epithelial ovarian cancer in Taiwanese women with a new surgico-pathological diagnosis of endometriosis

Table 4 Incidence and crude and adjusted risk of invasive epithelial ovarian cancer, according to age

	Age < 30 years (n =3148)		Age 30-39 years (n = 9310)		Age 40-49 years (n = 13747)		Age ≥ 50 years (n = 3520)
	Patients	Controls	Patients	Controls	Patients	Controls	Patients	Controls
Diagnosis of EOC
Yes	2	3	10	4	18	22	9	7
No	571	2572	1781	7515	3005	10702	549	2955
IR	4.99	1.78	9.89	0.96	10.66	3.38	35.81	5.80
Crude HR (95% CI)	2.80 (0.47-16.74)	1.00	13.80 (3.80-50.11)^**	1.00	3.03 (1.62-5.64)^*	1.00	6.74 (2.51-18.10)^*	1.00
Adjusted HR (95% CI)	3.34 (0.54-20.60)	1.00	19.41 (5.02-75.10)^**	1.00	3.41 (1.76-6.61)^*	1.00	9.63 (3.27-28.37)^**	1.00

Patients: women with endometriosis; Controls: women without endometriosis; EOC: epithelial ovarian cancer; IR: incidence rate (incidence per 10,000 person-years); HR: hazard ratio; CI: confidence interval; *P < 0.001, **P < 0.0001.

ISSN: 1471-2407