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Table 1 UCLA and meta-dataset analysis shows significantly earlier age of MPNST onset in NF-1 patients compared to spontaneous MPNST patients

From: Gender dimorphism and age of onset in malignant peripheral nerve sheath tumor preclinical models and human patients

Dataset Disease Male median age (n) Female median age (n) Male vs. female Wilcox p value Overall median age (n) NF-1 vs. spont. Wilcox p value
UCLA NF-1 31 yrs (19) 39 yrs (11) 0.09 33 yrs (30) 0.007
Spont. 37 yrs (42) 40 yrs (41) 0.25 39 yrs (83)
Others NF-1 29 yrs (230) 27 yrs (266) 0.11 28 yrs (496) <0.0001
  Spont. 43 yrs (221) 39 yrs (199) 0.88 41 yrs (420)  
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