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Table 1 UCLA and meta-dataset analysis shows significantly earlier age of MPNST onset in NF-1 patients compared to spontaneous MPNST patients

From: Gender dimorphism and age of onset in malignant peripheral nerve sheath tumor preclinical models and human patients

Dataset

Disease

Male median age (n)

Female median age (n)

Male vs. female Wilcox p value

Overall median age (n)

NF-1 vs. spont. Wilcox p value

UCLA

NF-1

31 yrs (19)

39 yrs (11)

0.09

33 yrs (30)

0.007

Spont.

37 yrs (42)

40 yrs (41)

0.25

39 yrs (83)

Others

NF-1

29 yrs (230)

27 yrs (266)

0.11

28 yrs (496)

<0.0001

 

Spont.

43 yrs (221)

39 yrs (199)

0.88

41 yrs (420)

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