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Table 1 Patient characteristics

From: Multicenter phase II study of Apatinib in non-triple-negative metastatic breast cancer

Characteristics

p value

Median age, range (years)

49(35, 62)

ECOG status, n (%)

 

 0

7(18.4)

 1

31(81.6)

ER status, n (%)

 

 Negative

8(21.1)

 Positive

30(78.9)

PR status, n (%)

 

 Negative

17(44.7)

 Positive

21(55.3)

HER2 status, n (%)

 

 Positive

9(23.7)

 Negative

23(60.5)

 Unknown

6(15.8)

Number of prior chemotherapy regimens, n (%)

 

 1

8(21.1)

 2

17(44.7)

 3

10(26.3)

 4

3(7.9)

Prior chemotherapy, n (%)

 

 Anthracycline + taxanes

38(100)

 Capecitabine

28(73.7)

 Vinorelbin

16(42.1)

 Gemcitabine

16(42.1)

Metastatic sites, n (%)

 

 Liver

25(65.8)

 Lymph nodes

21(55.3)

 Lung

17(44.7)

 Bone

14(36.8)

 Chest wall

9(23.7)

 Skin

1(2.6)

 Adrenal

1(2.6)

Visceral metastasis, n(%)

 

 Yes

5(13.2)

 No

33(86.8)

  1. ECOG, Eastern Cooperative Oncology Group.
  2. ER, estrogen receptor; PR, progesterone receptor.
  3. HER2, human epidermal growth factor receptor 2.