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Table 3 List of genes that statistically distinguish the hyperthermic response of three breast cancer lines from the mammary epithelial cells in the H’ vs H analysis

From: A genomics approach to identify susceptibilities of breast cancer cells to “fever-range” hyperthermia

Gene Symbol

Gene Name

Accession Number

MCF-7

MDA-231

MDA-468

RN7SK

RNA, 7SK small nuclear

NR_001445.1

68.5

64.5

73.5

RN5S9

RNA, 5S ribosomal 9

NR_023371.1

54.5

64.7

64.9

RNU1-3

RNA, U1 small nuclear 3

NR_004408.1

44.2

27.9

30.3

RNU1G2

RNA, U1 small nuclear 4

NR_004426.1

42.5

26.4

28.5

KIAA1666

RIMS binding protein 3

XM_942124.2

38.5

36.1

41.6

RNU1-5

RNA, U1 small nuclear 5

NR_004400.1

36.5

25.1

28.1

SNORD3D

Small nucleolar RNA, C/D box 3D

NR_006882.1

34.8

43.3

47.2

RNU1A3

RNA, U1 small nuclear 1

NR_004430.1

30.2

19.9

20.3

SNORD3A

Small nucleolar RNA, C/D box 3A

NR_006880.1

30.1

42.6

43.8

SNORD3C

Small nucleolar RNA, C/D box 3C

NR_006881.1

28.4

30.9

34.7

RNY5

RNA, Ro-associated Y5

NR_001571.2

27.8

4.6

4.3

LOC100008589

RNA28S5 RNA, 28S ribosomal 5

NR_003287.1

27.2

28.9

30.9

LOC100132564

Hypothetical Protein LOC100132564

XM_001713808.1

26.7

26.5

27.3

LOC100132394

Hypothetical Protein

XP_001713861.1

23.8

23.1

22.9

RNU4-1

RNA, U4 small nuclear 1

NR_003925.1

18.5

11.6

13.1

RNU6ATAC

RNA, U6atac small nuclear (U12-dependent splicing)

NR_023344.1

16.3

11.8

12.4

LOC100134364

Hypothetical Protein LOC100134364

XM_001713810.1

15.9

15.5

17.2

HIST2H2AA3

Histone cluster 2, H2aa3

NM_003516.2

15.3

3.2

3.1

HIST2H2AA4

Histone cluster 2, H2aa4

NM_001040874.1

13.4

3.1

2.8

MIR1974

MicroRNA 1974

NR_031738.1

12.8

24.1

24.5

RMRP

RNA component of mitochondrial RNA processing endoribonuclease

NR_003051.2

12.1

14.1

15.6

RNA18S5

RNA18S5 RNA, 18S ribosomal 5

NR_003286.1

11.4

11.9

12.6

RNU4-2

RNA, U4 small nuclear 2

NR_003137.2

10.7

5.7

6.3

SCARNA20

Small Cajal body-specific RNA 20

NR_002999.2

7.7

3.2

3.1

LOC441763

Hypothetical Protein LOC441763

XM_930284.1

7.4

5.9

7.2

LOC728688

Ubiquitin-like, containing PHD and RING finger domains

XM_001724542.1

6.6

6.1

7.3

VTRNA1-1

Vault RNA 1-1

NR_026703.1

6.5

4.4

4.1

RNU6-1

RNA, U6 small nuclear 1

NR_004394.1

6.3

6.9

7.3

RNU6-15

RNA, U6 small nuclear 15

NR_028372.1

6.3

6.2

7.1

ALB

Albumin

NM_000477.3

4.9

5.3

5.5

HIST1H4H

Histone cluster 1, H4h

NM_003543.3

4.9

2.9

2.9

HIST2H4A

Histone cluster 2, H4a

NM_003548.2

4.6

5.1

4.7

TRK1

Transfer RNA lysine 1 (anticodon UUU)

NR_001449.1

4.6

3.5

3.8

SNORD46

Small nucleolar RNA, C/D box 46

NR_000024.2

4.2

3.9

3.8

RNU4ATAC

RNA, U4atac small nuclear (U12-dependent splicing)

NR_023343.1

4.2

3.7

3.9

KREMEN2

Kringle containing transmembrane protein 2

NM_145348.1

4.1

2.9

2.8

RNU11

RNA, U11 small nuclear

NR_004407.1

3.8

2.8

2.9

SNORA57

Small nucleolar RNA, H/ACA box 57

NR_004390.1

3.8

4.9

5.2

RPPH1

Ribonuclease P RNA component H1

NR_002312.1

3.7

2.7

3.1

SCARNA13

Small Cajal body-specific RNA 13

NR_003002.1

3.7

4.3

4.9

RPL12P6

Ribosomal protein L12 pseudogene 6

XR_016704.2

3.5

2.4

4.1

LOC389787

Tumor protein, translationally-controlled 1 pseudogene

XM_497072.2

3.4

3.1

2.1

RPL10L

Ribosomal protein L10-like

NM_080746.2

3.3

3.6

3.7

SNORA7B

Small nucleolar RNA, H/ACA box 7B

NR_002992.2

3.2

4.8

5.1

LOC100132673

Ribosomal protein S2 pseudogene 28

XR_039018.1

3.1

2.3

2.6

RNY4

RNA, Ro-associated Y4

NR_004393.1

3.1

5.5

4.7

HOXB6

Homeobox B6

NM_018952.4

2.9

4.2

4.1

HIST1H4K

Histone cluster 1, H4k

NM_003541.2

2.9

3.2

3.3

SNORA12

Small nucleolar RNA, H/ACA box 12

NR_002954.1

2.9

2.4

2.3

LOC643031

MT-ND5 pseudogene 10

XM_926402.1

2.8

2.9

3.8

HIST2H4B

Histone cluster 2, H4b

NM_001034077.4

2.7

2.8

2.9

HIST2H3D

Histone cluster 2, H3d

NM_001123375.1

2.3

3.7

3.9

HIST1H2AC

Histone cluster 1, H2ac

NM_003512.3

2.3

2.9

2.7

EGR1

Early growth response 1

NM_001964.2

2.3

2.8

2.4

SNORA63

Small nucleolar RNA, H/ACA box 63

NR_002586.1

2.3

7.8

7.3

SNORD13

Small nucleolar RNA, C/D box 13

NR_003041.1

2.3

5.6

5.7

RNY1

RNA, Ro-associated Y1

NR_004391.1

2.1

4.4

4.1

HIST1H2AM

Histone cluster 1, H2am

NM_003514.2

2.1

3.1

3.5

MARCH7

Membrane-associated ring finger 7, E3 ubiquitin protein ligase

NM_022826.2

-2.0

-2.3

-2.3

GPBP1

GC-rich promoter binding protein 1

NM_022913.1

-2.0

-3.4

-2.9

RAB11FIP1

RAB11 family interacting protein 1 (class I)

NM_001002814.1

-2.0

-2.0

-2.8

CEBPG

CCAAT/enhancer binding protein (C/EBP), gamma

NM_001806.2

-2.0

-2.0

-2.5

ZWILCH

Zwilch kinetochore protein

NR_003105.1

-2.0

-2.7

-2.6

DDX18

DEAD (Asp-Glu-Ala-Asp) box polypeptide 18

NM_006773.3

-2.0

-2.6

-2.7

PTP4A1

Protein tyrosine phosphatase type IVA, member 1

NM_003463.3

-2.0

-2.9

-2.4

DDX3X

DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked

NM_001356.3

-2.0

-2.6

-2.3

CTCF

CCCTC-binding factor (zinc finger protein)

NM_006565.2

-2.0

-2.6

-2.3

SKAP2

src kinase associated phosphoprotein 2

NM_003930.3

-2.0

-2.3

-2.2

ANO6

Anoctamin 6

NM_001025356.1

-2.0

-2.3

-2.3

PPAT

Phosphoribosyl pyrophosphate amidotransferase

NM_002703.3

-2.0

-2.1

-2.3

USP34

Ubiquitin specific peptidase 34

NM_014709.3

-2.0

-2.1

-2.0

LHFPL2

Lipoma HMGIC fusion partner-like 2

NM_005779.1

-2.1

-2.1

-2.1

KIAA1147

KIAA1147

NM_001080392.1

-2.1

-2.1

-2.3

KIAA2010

SMEK homolog 1, suppressor of mek1 (Dictyostelium)

NM_032560.3

-2.1

-3.6

-3.0

DYRK1A

Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

NM_130438.1

-2.1

-2.5

-2.3

RBBP8

Retinoblastoma binding protein 8

NM_203291.1

-2.1

-2.6

-2.4

ANKIB1

Ankyrin repeat and IBR domain containing 1

NM_019004.1

-2.1

-2.5

-2.5

C12orf32

RAD9-HUS1-RAD1 interacting nuclear orphan 1

NM_031465.2

-2.1

-2.1

-2.1

FNIP1

Folliculin interacting protein 1

NM_001008738.2

-2.1

-2.0

-2.1

NAE1

NEDD8 activating enzyme E1 subunit 1

NM_001018160.1

-2.2

-2.0

-2.3

RSBN1

Round spermatid basic protein 1

NM_018364.3

-2.2

-2.0

-2.3

SUPT16H

Suppressor of Ty 16 homolog (S. cerevisiae)

NM_007192.2

-2.2

-2.1

-2.2

TMED10

Transmembrane emp24-like trafficking protein 10 (yeast)

NM_006827.5

-2.2

-3.6

-2.9

PPP1CB

Protein phosphatase 1, catalytic subunit, beta isozyme

NM_206876.1

-2.2

-2.4

-2.7

ARL6IP1

ADP-ribosylation factor-like 6 interacting protein 1

NM_015161.1

-2.2

-2.8

-2.7

ASNSD1

Asparagine synthetase domain containing 1

NM_019048.1

-2.2

-2.9

-2.5

NRBF2P4

Nuclear receptor binding factor 2 pseudogene 4

XM_001127763.1

-2.2

-2.6

-2.4

TTC37

Tetratricopeptide repeat domain 37

NM_014639.2

-2.2

-2.6

-2.2

DICER1

Dicer 1, ribonuclease type III

NM_030621.2

-2.2

-2.6

-2.3

UBE2G1

Ubiquitin-conjugating enzyme E2G 1

NM_003342.4

-2.2

-2.5

-2.4

LRPPRC

Leucine-rich pentatricopeptide repeat containing

NM_133259.2

-2.2

-2.4

-2.2

OTUD4

OTU domain containing 4

NM_199324.1

-2.2

-2.3

-2.2

FUBP3

Far upstream element (FUSE) binding protein 3

NM_003934.1

-2.2

-2.3

-2.2

FAM175B

Family with sequence similarity 175, member B

NM_032182.3

-2.2

-2.1

-2.1

DDX50

DEAD (Asp-Glu-Ala-Asp) box polypeptide 50

NM_024045.1

-2.2

-2.0

-2.1

PIGA

Phosphatidylinositol glycan anchor biosynthesis, class A

NM_020473.2

-2.2

-2.0

-2.2

FAM168B

Family with sequence similarity 168, member B

NM_001009993.2

-2.3

-2.0

-2.0

FBXO11

F-box protein 11

NM_025133.3

-2.3

-2.1

-2.5

SLC25A24

Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24

NM_013386.3

-2.3

-3.4

-2.5

NCKAP1

NCK-associated protein 1

NM_013436.3

-2.3

-3.3

-2.7

FBXW11

F-box and WD repeat domain containing 11

NM_033645.2

-2.3

-2.5

-2.7

SLC30A9

Solute carrier family 30 (zinc transporter), member 9

NM_006345.3

-2.3

-2.0

-2.7

ATAD2

ATPase family, AAA domain containing 2

NM_014109.2

-2.3

-2.8

-2.0

CSNK1A1

Casein kinase 1, alpha 1

NM_001025105.1

-2.3

-2.5

-2.2

CHUK

Conserved helix-loop-helix ubiquitous kinase

NM_001278.3

-2.3

-2.2

-2.3

ATP6V1C1

ATPase, H?+?transporting, lysosomal 42 kDa, V1 subunit C1

NM_001695.4

-2.3

-2.1

-2.4

CUL2

Cullin 2

NM_003591.2

-2.3

-2.2

-2.1

BRMS1L

Breast cancer metastasis-suppressor 1-like

NM_032352.3

-2.3

-2.1

-2.0

UBQLN1

Ubiquilin 1

NM_013438.3

-2.3

-2.1

-2.1

OPA1

Optic atrophy 1 (autosomal dominant)

NM_015560.1

-2.4

-2.7

-2.6

EFR3A

EFR3 homolog A (S. cerevisiae)

NM_015137.3

-2.4

-2.3

-3.2

BAT2D1

Proline-rich coiled-coil 2C

NM_015172.3

-2.4

-2.5

-2.1

OSBPL9

Oxysterol binding protein-like 9

NM_148906.1

-2.4

-2.6

-2.5

CDR2

Cerebellar degeneration-related protein 2, 62 kDa

NM_001802.1

-2.4

-2.3

-2.2

KPNA4

Karyopherin alpha 4 (importin alpha 3)

NM_002268.3

-2.4

-2.2

-2.4

ARL1

ADP-ribosylation factor-like 1

NM_001177.3

-2.4

-2.2

-2.3

DHX32

DEAH (Asp-Glu-Ala-His) box polypeptide 32

NM_018180.2

-2.4

-2.1

-2.3

RIOK3

RIO kinase 3

NM_003831.3

-2.4

-2.0

-2.1

C5orf51

Chromosome 5 open reading frame 51

NM_175921.4

-2.5

-2.8

-2.6

TJP1

Tight junction protein 1

NM_003257.3

-2.5

-2.4

-2.2

CSNK1G3

Casein kinase 1, gamma 3

NM_001031812.2

-2.5

-2.4

-2.3

PREI3

MOB family member 4, phocein

NM_199482.1

-2.5

-2.4

-2.4

KIAA0494

EF-hand calcium binding domain 14

NM_014774.1

-2.5

-2.3

-2.4

PRKRIR

Protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)

NM_004705.2

-2.5

-2.7

-3.0

LOC644363

LOC644363

XR_016912.2

-2.5

-2.6

-2.9

DCP2

DCP2 decapping enzyme homolog (S. cerevisiae)

NM_152624.4

-2.5

-2.5

-3.0

ROD1

Polypyrimidine tract binding protein 3

NM_005156.4

-2.5

-2.9

-3.2

CRK

v-crk sarcoma virus CT10 oncogene homolog (avian)

NM_016823.2

-2.5

-3.3

-2.8

PRKAR1A

Protein kinase, cAMP-dependent, regulatory, type I, alpha

NM_002734.3

-2.5

-2.6

-2.4

GPSM2

G-protein signaling modulator 2

NM_013296.3

-2.5

-2.2

-2.3

API5

Apoptosis inhibitor 5

NM_006595.2

-2.5

-2.1

-2.5

CRKL

v-crk sarcoma virus CT10 oncogene homolog (avian)-like

NM_005207.2

-2.5

-2.0

-2.6

CBL

Cbl proto-oncogene, E3 ubiquitin protein ligase

NM_005188.2

-2.5

-2.0

-2.2

SMG1

smg-1 homolog, phosphatidylinositol 3-kinase-related kinase interferon

NM_015092.3

-2.6

-2.9

-2.6

IRF2BP2

Regulatory factor 2 binding protein 2

NM_182972.2

-2.6

-2.7

-2.7

CNOT6

CCR4-NOT transcription complex, subunit 6

NM_015455.3

-2.6

-2.7

-2.6

THUMPD1

THUMP domain containing 1

NM_017736.3

-2.6

-2.6

-2.5

BMI1

BMI1 polycomb ring finger oncogene

NM_005180.5

-2.6

-2.4

-2.7

CDC2L6

Cyclin-dependent kinase 19

NM_015076.3

-2.6

-2.4

-2.8

TULP4

Tubby like protein 4

NM_001007466.1

-2.6

-2.3

-2.6

LARP4B

La ribonucleoprotein domain family, member 4B

NM_015155.1

-2.6

-2.3

-2.3

HECTD1

HECT domain containing E3 ubiquitin protein ligase 1

NM_015382.1

-2.6

-2.6

-2.4

CPSF2

Cleavage and polyadenylation specific factor 2, 100 kDa

NM_017437.1

-2.6

-2.8

-2.6

PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

NM_015200.1

-2.6

-2.6

-2.9

RIPK1

Receptor (TNFRSF)-interacting serine-threonine kinase 1

NM_003804.3

-2.6

-2.1

-2.4

DCAF6

DDB1 and CUL4 associated factor 6

NM_001017977.1

-2.6

-2.1

-2.4

KIAA1429

KIAA1429

NM_015496.3

-2.6

-2.0

-2.3

RUNX1

Runt-related transcription factor 1

NM_001754.3

-2.6

-2.1

-2.2

CEP135

Centrosomal protein 135 kDa

NM_025009.3

-2.6

-2.0

-2.2

MBNL1

Muscleblind-like splicing regulator 1

NM_207296.1

-2.6

-2.5

-2.2

RBPJ

Recombination signal binding protein for immunoglobulin kappa J region

NM_203284.1

-2.6

-2.4

-2.0

USP16

Ubiquitin specific peptidase 16

NM_006447.2

-2.6

-2.2

-2.1

TOMM20

Translocase of outer mitochondrial membrane 20 homolog (yeast)

NM_014765.1

-2.7

-2.3

-2.5

MTX3

Metaxin 3

NM_001010891.3

-2.7

-2.7

-2.6

RAPH1

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

NM_213589.1

-2.7

-2.6

-2.5

PHF20L1

PHD finger protein 20-like 1

NM_016018.4

-2.7

-2.6

-2.7

UBP1

Upstream binding protein 1 (LBP-1a)

NM_014517.3

-2.7

-2.5

-2.6

GBE1

Glucan (1,4-alpha-), branching enzyme 1

NM_000158.2

-2.7

-2.4

-2.3

CUL4B

Cullin 4B

NM_001079872.1

-2.7

-2.4

-2.4

PAPOLA

Poly(A) polymerase alpha

NM_001037281.1

-2.7

-2.4

-2.9

RNMT

RNA (guanine-7-) methyltransferase

NM_003799.1

-2.7

-2.1

-2.4

FBXO34

F-box protein 34

NM_017943.2

-2.7

-2.3

-2.1

DOCK7

Dedicator of cytokinesis 7

NM_033407.2

-2.7

-2.3

-2.1

BTBD3

BTB (POZ) domain containing 3

NM_014962.2

-2.7

-2.2

-2.1

C6orf130

O-acyl-ADP-ribose deacylase 1

NM_145063.2

-2.8

-2.3

-2.1

MRPL35

Mitochondrial ribosomal protein L35

NM_016622.2

-2.8

-2.2

-2.2

PUM2

Pumilio homolog 2 (Drosophila)

NM_015317.1

-2.8

-2.8

-2.8

NUDT21

Nudix (nucleoside diphosphate linked moiety X)-type motif 21

NM_007006.2

-2.8

-2.7

-2.3

ICK

Intestinal cell (MAK-like) kinase

NM_016513.3

-2.8

-2.7

-2.5

RBM17

RNA binding motif protein 17

NM_032905.3

-2.8

-2.4

-2.1

RMI1

RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)

NM_024945.2

-2.9

-2.4

-2.1

MAP2K4

Mitogen-activated protein kinase kinase 4

NM_003010.2

-2.9

-2.8

-2.8

G3BP2

GTPase activating protein (SH3 domain) binding protein 2

NM_203504.1

-2.9

-2.5

-2.5

NAMPT

Nicotinamide phosphoribosyltransferase

NM_005746.2

-2.9

-2.7

-2.1

BEND7

BEN domain containing 7

NM_001100912.1

-2.9

-2.2

-2.1

FEZ2

Fasciculation and elongation protein zeta 2 (zygin II)

NM_005102.2

-3.0

-2.2

-2.2

ARL4A

ADP-ribosylation factor-like 4A

NM_001037164.1

-3.0

-2.4

-2.2

SOCS4

Suppressor of cytokine signaling 4

NM_080867.2

-3.0

-3.0

-2.6

STAG2

Stromal antigen 2

NM_001042750.1

-3.0

-2.9

-2.5

C14orf32

Mitogen-activated protein kinase 1 interacting protein 1-like

NM_144578.2

-3.0

-2.9

-2.9

PPP3CB

Protein phosphatase 3, catalytic subunit, beta isozyme

NM_021132.1

-3.0

-2.4

-2.6

RBM25

RNA binding motif protein 25

NM_021239.1

-3.0

-2.4

-2.5

ERI1

Exoribonuclease 1

NM_153332.3

-3.0

-2.0

-2.3

NRD1

Nardilysin (N-arginine dibasic convertase)

NM_002525.1

-3.0

-2.4

-2.1

E2F3

E2F transcription factor 3

NM_001949.2

-3.0

-2.0

-2.0

ANKRD28

Ankyrin repeat domain 28

NM_015199.2

-3.1

-2.3

-2.2

ZAK

Sterile alpha motif and leucine zipper containing kinase AZK

NM_133646.2

-3.1

-3.1

-3.4

HNRPR

Heterogeneous nuclear ribonucleoprotein R

NM_005826.2

-3.1

-2.9

-2.1

TMEM123

Transmembrane protein 123

NM_052932.2

-3.1

-2.8

-2.3

FAM178A

Family with sequence similarity 178, member A

NM_018121.3

-3.1

-2.7

-2.6

EML4

Echinoderm microtubule associated protein like 4

NM_019063.2

-3.1

-2.6

-2.6

FOXJ3

Forkhead box J3

NM_014947.3

-3.1

-2.5

-2.5

NT5DC3

5'-nucleotidase domain containing 3

NM_016575.1

-3.1

-2.3

-2.6

LPP

LIM domain containing preferred translocation partner in lipoma

NM_005578.2

-3.1

-2.2

-3.5

RND3

Rho family GTPase 3

NM_005168.3

-3.1

-2.0

-2.2

WDR36

WD repeat domain 36

NM_139281.2

-3.1

-2.0

-2.2

CDCA1

NUF2, NDC80 kinetochore complex component

NM_145697.1

-3.1

-2.5

-2.0

PRSS23

Protease, serine, 23

NM_007173.4

-3.2

-2.3

-2.0

ERCC6L

Excision repair cross-complementing rodent repair deficiency, complementation group 6-like

NM_017669.2

-3.2

-2.3

-2.0

FAM122B

Family with sequence similarity 122B

NM_032448.1

-3.3

-2.5

-2.0

CKAP5

Cytoskeleton associated protein 5

NM_001008938.1

-3.3

-2.2

-2.1

CGGBP1

CGG triplet repeat binding protein 1

NM_001008390.1

-3.3

-2.8

-3.5

TBL1XR1

Transducin (beta)-like 1 X-linked receptor 1

NM_024665.3

-3.3

-3.1

-2.7

LOC644799

LOC644799

XM_934554.1

-3.3

-3.0

-2.5

DCK

Deoxycytidine kinase

NM_000788.1

-3.3

-2.8

-2.2

SERBP1

SERPINE1 mRNA binding protein 1

NM_030666.2

-3.3

-2.1

-3.3

PPP1CC

Protein phosphatase 1, catalytic subunit, gamma isozyme

NM_002710.1

-3.3

-2.2

-2.1

KIF5B

Kinesin family member 5B

NM_004521.1

-3.4

-4.1

-3.3

AFF4

AF4/FMR2 family, member 4

NM_014423.3

-3.4

-3.6

-3.5

MPP5

Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)

NM_022474.2

-3.4

-3.1

-2.7

IPO5

Importin 5

NM_002271.4

-3.4

-2.6

-2.2

HNRNPR

Heterogeneous nuclear ribonucleoprotein R

NM_005826.3

-3.4

-2.6

-2.3

CP110

Centriolar coiled coil protein 110 kDa

NM_014711.3

-3.4

-2.5

-2.5

FEM1C

fem-1 homolog c (C. elegans)

NM_020177.2

-3.4

-2.4

-2.5

PHTF1

Putative homeodomain transcription factor 1

NM_006608.1

-3.4

-2.3

-2.1

RAD51AP1

RAD51 associated protein 1

NM_006479.3

-3.4

-2.2

-2.0

MAPRE1

Microtubule-associated protein, RP/EB family, member 1

NM_012325.1

-3.4

-2.1

-2.1

TMPO

Thymopoietin

NM_003276.1

-3.5

-3.1

-2.3

LACTB

Lactamase, beta

NM_032857.2

-3.5

-2.3

-2.3

DDX46

DEAD (Asp-Glu-Ala-Asp) box polypeptide 46

NM_014829.2

-3.5

-2.3

-2.4

SPEN

Spen homolog, transcriptional regulator (Drosophila)

NM_015001.2

-3.5

-2.0

-2.7

TMEM19

Transmembrane protein 19

NM_018279.3

-3.5

-2.1

-2.0

CBFB

Core-binding factor, beta subunit

NM_001755.2

-3.5

-2.2

-2.2

IPO8

Importin 8

NM_006390.2

-3.5

-2.2

-2.1

WT1

Wilms tumor 1

NM_024426.3

-3.5

-2.4

-2.1

CKAP2

Cytoskeleton associated protein 2

NM_001098525.1

-3.6

-3.0

-2.4

WEE1

WEE1 homolog (S. pombe)

NM_003390.2

-3.6

-2.8

-2.7

PDCD6IP

Programmed cell death 6 interacting protein

NM_013374.3

-3.6

-2.7

-2.3

ZNF788

Zinc finger family member 788

XR_041527.1

-3.6

-2.6

-2.3

RAP2A

RAP2A, member of RAS oncogene family

NM_021033.5

-3.6

-2.3

-2.7

MGEA5

Meningioma expressed antigen 5 (hyaluronidase)

NM_012215.2

-3.6

-2.1

-2.7

UBE3A

Ubiquitin protein ligase E3A

NM_000462.2

-3.6

-2.0

-2.8

PLK4

Polo-like kinase 4

NM_014264.3

-3.7

-3.8

-3.2

RP2

Retinitis pigmentosa 2 (X-linked recessive)

NM_006915.1

-3.7

-2.9

-2.5

SETD2

SET domain containing 2

NM_014159.4

-3.7

-2.7

-2.8

KLHL5

Kelch-like family member 5

NM_001007075.1

-3.7

-2.4

-2.6

KBTBD2

Kelch repeat and BTB (POZ) domain containing 2

NM_015483.1

-3.7

-3.7

-3.1

USP9X

Ubiquitin specific peptidase 9, X-linked

NM_001039591.2

-3.8

-2.8

-2.4

RAB23

RAB23, member RAS oncogene family

NM_016277.3

-3.8

-2.6

-2.5

DR1

Down-regulator of transcription 1, TBP-binding (negative cofactor 2)

NM_001938.2

-3.8

-2.3

-2.2

RAB8B

RAB8B, member RAS oncogene family

NM_016530.2

-3.8

-2.3

-2.5

ZNF451

Zinc finger protein 451

NM_001031623.2

-3.8

-2.2

-2.4

ZZZ3

Zinc finger, ZZ-type containing 3

NM_015534.4

-3.9

-3.1

-3.3

CDC2

Cyclin-dependent kinase 1

NM_001786.2

-4.0

-2.9

-2.3

ZFP106

Zinc finger protein 106

NM_022473.1

-4.0

-3.0

-2.5

CAB39

Calcium binding protein 39

NM_016289.2

-4.0

-2.0

-3.1

TNPO1

Transportin 1

NM_153188.2

-4.0

-2.9

-2.5

MAP3K4

Mitogen-activated protein kinase kinase kinase 4

NM_005922.2

-4.1

-2.3

-2.7

ECT2

Epithelial cell transforming sequence 2 oncogene

NM_018098.4

-4.1

-2.3

-2.0

TMED5

Transmembrane emp24 protein transport domain containing 5

NM_016040.3

-4.1

-2.3

-2.1

SEH1L

SEH1-like (S. cerevisiae)

NM_001013437.1

-4.1

-2.7

-2.5

NCAPG2

Non-SMC condensin II complex, subunit G2

NM_017760.5

-4.2

-2.7

-2.2

USP1

Ubiquitin specific peptidase 1

NM_001017416.1

-4.2

-2.3

-2.4

OXSR1

Oxidative-stress responsive 1

NM_005109.2

-4.2

-2.3

-2.4

PTPN12

Protein tyrosine phosphatase, non-receptor type 12

NM_002835.2

-4.2

-2.8

-2.8

CMPK1

Cytidine monophosphate (UMP-CMP) kinase 1, cytosolic

NM_016308.1

-4.2

-2.5

-2.4

PAFAH1B1

Platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45 kDa)

NM_000430.2

-4.3

-3.8

-3.1

PURB

Purine-rich element binding protein B

NM_033224.3

-4.3

-2.5

-3.5

STK4

Serine/threonine kinase 4

NM_006282.2

-4.3

-2.3

-3.3

KATNAL1

Katanin p60 subunit A-like 1

NM_001014380.1

-4.3

-3.1

-2.9

NIN

Ninein (GSK3B interacting protein)

NM_020921.3

-4.3

-2.7

-2.4

LOC283267

Long intergenic non-protein coding RNA 294

NR_015451.1

-4.3

-2.6

-2.6

CCNB1

Cyclin B1

NM_031966.2

-4.3

-2.4

-2.2

YAP1

Yes-associated protein 1

NM_006106.2

-4.3

-2.0

-2.5

XPO1

Exportin 1 (CRM1 homolog, yeast)

NM_003400.3

-4.4

-2.9

-2.6

PTPN11

Protein tyrosine phosphatase, non-receptor type 11

NM_002834.3

-4.4

-2.4

-2.5

PHF3

PHD finger protein 3

NM_015153.1

-4.4

-2.2

-2.6

VMA21

Vacuolar H?+?-ATPase homolog (S. cerevisiae)

NM_001017980.2

-4.4

-2.2

-2.3

CHST15

Carbohydrate sulfotransferase 15

NM_015892.2

-4.4

-2.0

-2.5

RUNX2

Runt-related transcription factor 2

NM_001024630.2

-4.5

-2.7

-2.4

KIF14

Kinesin family member 14

NM_014875.1

-4.6

-3.4

-2.2

EHBP1

EH domain binding protein 1

NM_015252.2

-4.6

-2.7

-2.6

NEK2

NIMA-related kinase 2

NM_002497.2

-4.6

-2.7

-2.6

STK38

Serine/threonine kinase 38

NM_007271.2

-4.7

-3.2

-2.4

ZNF22

Zinc finger protein 22

NM_006963.3

-4.7

-3.2

-2.8

SPRY4

Sprouty homolog 4 (Drosophila)

NM_030964.2

-4.7

-2.0

-2.1

GMFB

Glia maturation factor, beta

NM_004124.2

-4.8

-2.2

-3.2

GCNT1

Glucosaminyl (N-acetyl) transferase 1, core 2

NM_001097635.1

-4.8

-3.1

-2.4

HERC4

HECT and RLD domain containing E3 ubiquitin protein ligase 4

NM_022079.2

-4.8

-3.1

-2.6

PPP4R1

Protein phosphatase 4, regulatory subunit 1

NM_005134.2

-4.8

-2.1

-2.6

SMAD5

SMAD family member 5

NM_005903.5

-4.9

-2.2

-3.2

GNG12

guanine nucleotide binding protein (G protein), gamma 12

NM_018841.4

-4.9

-2.8

-2.1

SMARCA1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

NM_003069.2

-4.9

-2.8

-2.3

DEK

DEK oncogene

NM_003472.2

-4.9

-2.5

-2.4

FAM107B

Family with sequence similarity 107, member B

NM_031453.2

-5.1

-3.1

-2.1

SUZ12

Suppressor of zeste 12 homolog (Drosophila)

NM_015355.1

-5.1

-2.8

-2.7

OSBPL3

Oxysterol binding protein-like 3

NM_145322.1

-5.1

-2.7

-2.7

UBE3C

Ubiquitin protein ligase E3C

NM_014671.1

-5.1

-2.7

-2.7

HSDL2

Hydroxysteroid dehydrogenase like 2

NM_032303.3

-5.1

-2.5

-2.5

C14orf106

MIS18 binding protein 1

NM_018353.3

-5.1

-2.3

-2.3

MBP

Myelin basic protein

NM_001025100.1

-5.1

-2.0

-2.3

GPAM

Glycerol-3-phosphate acyltransferase, mitochondrial

NM_020918.3

-5.2

-3.1

-2.7

RASA1

RAS p21 protein activator (GTPase activating protein) 1

NM_002890.1

-5.2

-2.9

-3.1

KIF11

Kinesin family member 11

NM_004523.2

-5.2

-3.3

-3.1

FBXO5

F-box protein 5

NM_012177.2

-5.2

-3.1

-2.3

CENPE

Centromere protein E, 312 kDa

NM_001813.2

-5.2

-2.6

-2.3

PAK2

p21 protein (Cdc42/Rac)-activated kinase 2

NM_002577.3

-5.3

-3.3

-3.6

IL7R

Interleukin 7 receptor

XM_937367.1

-5.3

-2.8

-2.2

ENC1

Ectodermal-neural cortex 1 (with BTB domain)

NM_003633.1

-5.3

-2.6

-2.3

SOX9

SRY (sex determining region Y)-box 9

NM_000346.2

-5.3

-2.5

-2.3

ASXL1

Additional sex combs like 1 (Drosophila) (ASXL1), TV1

NM_015338.4

-5.3

-2.0

-2.0

C10orf6

Family with sequence similarity 178, member A

NM_018121.2

-5.5

-3.2

-3.4

CEP55

Centrosomal protein 55 kDa

NM_018131.3

-5.6

-3.4

-2.6

NMT2

N-myristoyltransferase 2

NM_004808.2

-5.6

-2.4

-2.0

PPPDE1

Desumoylating isopeptidase 2

NM_016076.3

-5.8

-2.4

-2.9

TGFBR2

Transforming growth factor, beta receptor II (70/80 kDa)

NM_001024847.1

-6.0

-2.1

-2.2

MID1

Midline 1 (Opitz/BBB syndrome)

NM_033290.2

-6.2

-2.9

-2.1

FNDC3B

Fibronectin type III domain containing 3B

NM_001135095.1

-6.2

-2.8

-2.6

BIRC2

Baculoviral IAP repeat containing 2

NM_001166.3

-6.2

-2.9

-2.7

FAM3C

Family with sequence similarity 3, member C

NM_001040020.1

-6.2

-2.4

-2.0

KIF23

Kinesin family member 23

NM_004856.4

-6.3

-3.4

-2.7

CLIC4

Chloride intracellular channel 4

NM_013943.1

-6.3

-3.4

-2.6

PDGFC

Platelet derived growth factor C

NM_016205.1

-6.4

-2.4

-2.0

PRKCA

Protein kinase C, alpha

NM_002737.2

-6.7

-2.5

-2.2

NCAPG

Non-SMC condensin I complex, subunit G

NM_022346.3

-7.1

-2.6

-2.1

CENPF

Centromere protein F, 350/400 kDa

NM_016343.3

-7.4

-2.9

-2.7

GCNT2

Glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)

NM_001491.2

-7.4

-2.5

-2.5

C14orf135

Pecanex-like 4 (Drosophila)

NM_022495.5

-7.5

-2.7

-2.5

PBK

PDZ binding kinase

NM_018492.2

-7.8

-3.3

-2.4

TOP2A

Topoisomerase (DNA) II alpha 170 kDa

NM_001067.2

-8.1

-3.8

-2.7

CAV2

Caveolin 2

NM_001233.3

-8.1

-2.3

-2.5

SERTAD2

SERTA domain containing 2

NM_014755.1

-8.3

-3.1

-3.6

ACSL4

Acyl-CoA synthetase long-chain family member 4

NM_004458.1

-8.5

-2.5

-2.5

FAM83D

Family with sequence similarity 83, member D

NM_030919.2

-9.2

-4.3

-3.8

CDK6

Cyclin-dependent kinase 6

NM_001259.5

-9.4

-3.1

-4.1

FRMD6

FERM domain containing 6

NM_152330.3

-9.5

-3.1

-2.4

SNAPC1

Small nuclear RNA activating complex, polypeptide 1, 43 kDa

NM_003082.2

-9.8

-2.3

-2.0

CALD1

Caldesmon 1

NM_033140.2

-9.9

-2.1

-2.5

BCAT1

Branched chain amino-acid transaminase 1, cytosolic

NM_005504.4

-10.2

-5.6

-4.2

DLGAP5

Discs, large (Drosophila) homolog-associated protein 5

NM_014750.3

-10.4

-3.1

-2.4

ANLN

Anillin, actin binding protein

NM_018685.2

-10.9

-3.1

-2.2

TACC1

Transforming, acidic coiled-coil containing protein 1

NM_006283.1

-11.1

-2.7

-2.6

AP1S2

Adaptor-related protein complex 1, sigma 2 subunit

NM_003916.3

-11.5

-2.5

-2.1

CTNNAL1

Catenin (cadherin-associated protein), alpha-like 1

NM_003798.2

-13.9

-3.1

-2.1

DCBLD2

Discoidin, CUB and LCCL domain containing 2

NM_080927.3

-14.5

-3.1

-2.6

CAV1

Caveolin 1, caveolae protein, 22 kDa

NM_001753.3

-20.1

-3.3

-2.8