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Table 3 Multivariate Cox regression analysis for all post-treatment patients and post-treatment patients with a treatment response of VGPR/CR

From: MALAT1 long non-coding RNA is overexpressed in multiple myeloma and may serve as a marker to predict disease progression

   

PFS ≤18 months (N = 18)

PFS >18 months (N = 18)

Cox regression analysis

OR

95% CI

P value

All patients (N = 36)

Auto-HSCT in 1st line treatment, n

9

2(11.1%)

7(38.9%)

0.22

0.05-0.97

0.046

Difference in △CT ≤1.5, n

17

13(72.2%)

4(22.2%)

4.89

1.73-13.86

0.003

   

PFS ≤18 months (N = 15)

PFS >18 months (N = 18)

   

Patients with VGPR/CR (N = 33)

Auto-HSCT in 1st line treatment, n

9

2(13.3%)

7(38.9%)

0.24

0.05-1.09

0.066

Difference in △CT ≤1.5, n

14

10(66.7%)

4(22.2%)

4.38

1.48-12.99

0.008

  1. OR, Odds ratio; CI, confidential interval; Auto-HSCT, autologous hematopoietic stem-cell transplantation; CR, complete response; VGPR, very good partial response; PFS, progression-free survival.