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Figure 1 | BMC Cancer

Figure 1

From: MALAT1 long non-coding RNA is overexpressed in multiple myeloma and may serve as a marker to predict disease progression

Figure 1

Expression of MALAT1 during treatment and follow-up in two representative patients. The first patient (Patient 1) had a high expression of MALAT1 initially, which then decreased after successful induction chemotherapy and autologous peripheral blood stem cell transplantation, 9 months after the time of diagnosis. At 18 months, disease relapse was accompanied by an increase in MALAT1 expression. After salvage treatment, the disease was controlled and the expression of MALAT1 decreased. Eventually, the disease progressed and the expression of MALAT1 increased. The second patient (Patient 2) received induction chemotherapy followed by peripheral blood stem cell transplantation. The expression of MALAT1 decreased markedly after the treatment achieved complete remission. The disease status remained in remission during the follow-up period and was accompanied by a low expression of MALAT1.

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