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Table 2 Patient and tumor characteristics

From: Oxaliplatin-based versus irinotecan-based hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with peritoneal metastasis from appendiceal and colorectal cancer: a retrospective analysis

 

Overall

OX

IRI

p-value

Number of patients [n]

32

20

12

 

I. Patient characteristics

Mean age (range) [y]

54 (20-68)

53 (20-68)

54 (42-66)

0.842

Sex [n] - male

14 (43.8%)

9 (45.0%)

5 (41.7%)

 

    - female

18 (56.3%)

11 (55.0%)

7 (52.8%)

1.000

ASA score [n]

    

- ASA I

3 (9.4%)

2 (10.0%)

1 (8.3%)

1.000

- ASA II

23 (71.9%)

14 (70.0%)

9 (75.0%)

1.000

- ASA III

6 (18.8%)

4 (20.0%)

2 (16.7%)

1.000

II. Localization of primary tumor

Appendix

11 (34.4%)

9 (45.0%)

2 (16.7%)

0.139

Colon

7 (21.9%)

2 (10.0%)

5 (41.7%)

0.073

Sigma

10 (31.3%)

7 (35.0%)

3 (25.0%)

0.702

Rectum

4 (12.5%)

2 (10.0%)

2 (16.7%)

0.620

III. Initial TNM classification

T2

1* (3.2%)

1 (5.0%)

0**

1.000

T3

10* (32.3%)

6 (30.0%)

4** (36.4%)

1.000

T4

20* (64.5%)

13 (65.0%)

7** (63.7%)

1.000

N0

16* (51.6%)

13 (65.0%)

3** (27.3%)

0.066

N1

5* (16.1%)

2 (10.0%)

3** (27.3%)

0.317

N2

10* (32.3%)

5 (25.0%)

5** (45.5%)

0.423

M1

22 (68.8%)

14 (70.0%)

8 (66.7%)

1.000

G1

5 (15.6%)

5 (25.0%)

0

0.130

G2

11 (34.4%)

7 (35.0%)

4 (33.3%)

1.000

G3

16 (50.0%)

8 (40.0%)

8 (66.7%)

0.273

IV. Further tumor characteristics

Mean PCI (range)

13 (2-28)

13 (4-28)

12 (2-28)

0.630

Synchronous PM

16 (50.0%)

10 (50.0%)

6 (50.0%)

1.000

Metachronous PM

10 (31.3%)

6 (30.0%)

4 (33.3%)

1.000

Recurrent disease

6 (18.8%)

4 (20.0%)

2 (16.7%)

1.000

Liver metastasis

4 (12.5%)

1 (5.0%)

3 (25.0%)

0.271

V. Medical history

Previous abdominal surgery

14 (43.8%)

9 (45.0%)

5 (41.7%)

1.000

Previous oncologic surgery

24 (75.0%)

14 (70.0%)

10 (83.3%)

0.676

Previous CRS and HIPEC

5 (15.6%)

3 (15.0%)

2 (16.7%)

1.000

Previous chemotherapy

28 (87.5%)

16 (80.0%)

12 (100%)

0.271

Previous systemic oxaliplatin

17 (53.1%)

11 (55.0%)

6 (50%)

1.000

  1. *n = 31, **n = 11.