The effect of the
tumor formation of SNU-478 cells.
In vivo tumor formation was examined by subcutaneously injecting SNU-478:VEC or SNU-478:KD2 cells into athymic nude mice. A. Mice were injected with SNU-478:VEC (left side) or SNU-478:KD2 (right side) cells and nursed for 21 days. B. Increase in tumor size measured after a week post injection as volume (mm3) every two days for 21 days. Results shown are means ± standard deviations of three mice (Student’s t-test, P = 0.021). B-insert. Resected tumors formed by SNU-478:VEC after 21 days post injection.