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Table 4 Determinants of HR-HPV persistence for women with normal or mild cervical abnormality, for the folate sub-set; results of a multivariate analysis

From: Tumour suppressor gene methylation and cervical cell folate concentration are determinants of high-risk human papillomavirus persistence: a nested case control study

Variable Odds ratio [95% CI] P value
Total sample   
Folate [ng/mg] 1.065 [1.012; 1.120] 0.015
HPV-16 infection 1.509 [1.022; 2.228] 0.038
Multiple HR-HPV infections 1.440 [1.026; 2.019] 0.036
Normal cervical cytology   
Age 1.031 [1.007; 1.055] 0.012
HPV-16 infection 1.915 [1.176; 3.119] 0.009
Multiple HR-HPV infections 1.570 [1.020; 2.416] 0.040
Mild cervical cytology   
Age 0.925 [0.872; 0.982] 0.010
Folate [ng/mg] 1.144 [1.020; 1.282] 0.021
HPV-52 infections 4.924 [1.310; 18.513] 0.018
  1. HPV persistence refers to any HR-HPV infection at follow-up.
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