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Table 8 Analysis of OS according to the 3 most common KRAS codon 12 and 13 mutations in 205 BRAF wt colorectal cancer patients by cox regression analysis

From: BRAF V600E mutation and KRAS codon 13 mutations predict poor survival in Chinese colorectal cancer patients

    

Univariate analysis

Multivariate analysis

KRAS

BRAF

Total N

No. of events

HR (95% CI)

P

HR (95% CI)

P

wt

wt

109

22

1

 

1

 

c.38G > A

wt

23

9

2.4 (1.1-5.3)

0.026

2.6 (1.2-5.8)

0.016

c.35G > A

wt

34

9

1.4 (0.6-3.0)

0.425

1.1 (0.5-2.4)

0.853

c.35G > T

wt

20

5

1.4 (0.5-3.6)

0.546

1.5 (0.6-4.0)

0.408

  1. NOTE: The multivariate cox regression model included the same set of covariates selected in Table 7. P-values ≤ 0.05 are in bold.
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BMC Cancer

ISSN: 1471-2407

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