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Table 8 Analysis of OS according to the 3 most common KRAS codon 12 and 13 mutations in 205 BRAF wt colorectal cancer patients by cox regression analysis

From: BRAF V600E mutation and KRAS codon 13 mutations predict poor survival in Chinese colorectal cancer patients

     Univariate analysis Multivariate analysis
KRAS BRAF Total N No. of events HR (95% CI) P HR (95% CI) P
wt wt 109 22 1   1  
c.38G > A wt 23 9 2.4 (1.1-5.3) 0.026 2.6 (1.2-5.8) 0.016
c.35G > A wt 34 9 1.4 (0.6-3.0) 0.425 1.1 (0.5-2.4) 0.853
c.35G > T wt 20 5 1.4 (0.5-3.6) 0.546 1.5 (0.6-4.0) 0.408
  1. NOTE: The multivariate cox regression model included the same set of covariates selected in Table 7. P-values ≤ 0.05 are in bold.