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Table 3 Differentially expressed miRNAs (p < 0.01) between HGSC, CCC and OSE verified by RT-qPCR

From: Global miRNA expression analysis of serous and clear cell ovarian carcinomas identifies differentially expressed miRNAs including miR-200c-3p as a prognostic marker

  HGSC vs. OSEa CCC vs. OSEa CCC vs. HGSCa
miRNAs p-values FC values p-values FC values p-values FC values
miR-134 8.7 × 10-11 -5.7b    3.1 × 10-6 4.3
miR-141-3p 1.7 × 10-18 40.3 7.2 × 10-11 45.3   
miR-182-5p 9.5 × 10-15 42.4 1.2 × 10-8 66.2   
miR-200a-3p 3.6 × 10-5 33.0 9.3 × 10-10 57.8   
miR-200a-5p 3.1 × 10-15 33.8 4.3 × 10-11 53.0   
miR-200b-3p 5.3 × 10-18 38.8 3.7 × 10-11 51.0   
miR-200c-3p 6.0 × 10-21 48.2 3.2 × 10-12 53.4   
miR-202-3p 1.3 × 10-14 -14.7    1.6 × 10-7 10.1
miR-205-5p 9.0 × 10-9 74.3    4.4 × 10-3 -8.4
miR-383 2.2 × 10-14 -36.6 9.8 × 10-10 -15.1 2.2 × 10-3 2.4
miR-424-5p 3.1 × 10-13 -10.7 3.5 × 10-4 -4.2 1.6 × 10-3 2.5
miR-508-5p    3.5 × 10-3 10.1 1.0 × 10-8 27.5
miR-509-3p      2.0 × 10-7 46.3
miR-509-5p 5.0 × 10-3 -4.1 2.4 × 10-3 13.3 1.3 × 10-8 54.7
miR-509-3-5p 1.1 × 10-4 -11.0    2.2 × 10-8 95.3
miR-510    2.5 × 10-3 9.0 8.7 × 10-10 32.9
miR-513a-5p    6.6 × 10-4 6.2 9.1 × 10-7 8.3
miR-514b-5p    9.7 × 10-5 12.1 2.3 × 10-9 25.8
  1. aHGSC: High-grade serous ovarian carcinoma. OSE: ovarian surface epithelium. CCC: Clear cell ovarian carcinoma. b‘-’ illustrates underexpression. FC: Fold change.