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Table 2 Differentially expressed miRNAs between HGSC, CCC and OSE of global miRNA expression profiling* selected for RT-qPCR validation

From: Global miRNA expression analysis of serous and clear cell ovarian carcinomas identifies differentially expressed miRNAs including miR-200c-3p as a prognostic marker

  HGSC vs. OSEa CCC vs. OSEa CCC vs. HGSCa
miRNAs p-values FC values p-value FC value p-value FC value
miR-134 8.3 × 10-8 -16.7b    1.0 × 10-4 5.8
miR-141-3p 1.1 × 10-11 46.1 2.4 × 10-10 34.9   
miR-182-5p 6.0 × 10-9 30.2 1.4 × 10-8 32.7   
miR-200a-3p 7.3 × 10-10 33.6 1.3 × 10-9 38.8   
miR-200a-5p 3.0 × 10-13 33.5 6.9 × 10-12 26.5   
miR-200b-3p 1.1 × 10-9 29.1 2.9 × 10-8 21.1   
miR-200c-3p 1.2 × 10-12 16.5 1.2 × 10-11 15.0   
miR-202-3p 8.0 × 10-6 -36.9    2.3 × 10-4 16.3
miR-205-5p 4.9 × 10-5 105.1    3.1 × 10-3 -23.1
miR-383 8.2 × 10-12 -33.7 1.5 × 10-11 -38.7   
miR-424-5p 2.6 × 10-9 -26.0 4.0 × 10-6 -10.1   
miR-508-5p    4.4 × 10-3 11.6 3.1 × 10-6 75.0
miR-509-3p 4.3 × 10-3 -10.3    2.6 × 10-6 83.4
miR-509-5p    5.6 × 10-4 11.4 1.8 × 10-6 34.0
miR-509-3-5p 3.9 × 10-3 -10.2    1.9 × 10-6 84.6
miR-510 9.3 × 10-3 -5.2 7.9 × 10-3 6.1 3.0 × 10-6 31.7
miR-513a-5p    4.8 × 10-3 7.4 4.1 × 10-6 33.5
miR-514b-5p 9.7 × 10-3 -6.5 3.8 × 10-3 9.8 1.3 × 10-6 63.6
  1. *Affymetrix GeneChip miRNA 2.0 Arrays. aHGSC: High-grade serous ovarian carcinoma. OSE: ovarian surface epithelium. CCC: Clear cell ovarian carcinoma. b‘-’ illustrates underexpression. FC: Fold change. P-values are calculated on original data (before FDR corrections).