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Table 1 Clinicopathological and laboratory information for patients selected for RT-qPCR analysis

From: Global miRNA expression analysis of serous and clear cell ovarian carcinomas identifies differentially expressed miRNAs including miR-200c-3p as a prognostic marker

Parameter HGSCa, n = 35 CCCa, n = 19
Age; mean ± SD (range) 64.0 ± 11.3 (45–87) 63.9 ± 15.3 (28–83)
Preoperative CA125 (kU/L); mean ± SD 3023 ± 4129 1438 ± 2198
FIGO stage I 0 10
II 0 3
III 25 5
IV 10 1
Residual disease 0 cm 3 13
<2 cm 9 4
>2 cm 23 2
Start of chemotherapy (days after surgery); mean ± SD 27.7 ± 11.6 25.7 ± 13.8
CA125 responseb Yes 31 15
No 1 0
Optimal CA125 normalizationb Yes 20 13
No 14 3
Median time (months) until progression (95% CI) 10 (7–13) NAc
Median time (months) until death (95% CI) 26 (18–34) 105 (35–175)
Status at last follow-upd NED 1 11
AWD 1 1
DOD 33 6
DOUC 0 1
  1. aHGSC: High-grade serous ovarian carcinoma; CCC: Clear cell ovarian carcinoma.
  2. bAccording to the GCIG criteria (http://www.gcig.igcs.org). For HGSC: Two patients who received no postoperative treatment due to poor general condition, one patient with preoperative CA125 < 70; For CCC: One patient who received no postoperative treatment due to poor condition, three patients with preoperative CA125 < 70.
  3. cCould not be calculated since the Kaplan-Meier survival curve stays above 50%.
  4. dNED = No evidence of disease; AWD = Alive with disease; DOD = Dead of disease; DOUC = Dead of unrelated cause.