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Table 1 Associations between clinicopathological parameters and either 17q23-25 amplification, miR-21 overexpression, or PTEN protein loss

From: MicroRNA-21 is a candidate driver gene for 17q23-25 amplification in ovarian clear cell carcinoma

Variable Cases (Total 28) 17q23-25 amplification miR-21 overexpression Loss of PTEN protein expression
   n = 9 P value n = 17 P value n = 13 P value
Age 6    4 >0.9999 5 0.0690
60 22 2 >0.9999 13   8  
  < 60   7      
Stage    0.6464   >0.9999 8 0.1977
  I-II 21 6   11   5  
  III-IV 7 3   4    
Lymph node status 7     >0.9999 4 0.6702
  Metastasis 21 3 0.6219 4   9  
  No metastasis   6   11    
Endometriosis   8 0.2143 15   10 0.6859
  Positive 20 1   2 0.0298 3  
  Negative 8       
Thrombosis 3 1 >0.9999 2 >0.9999 2 0.5833
  Positive 25 8   13   11  
  Negative        
  1. No correlations were observed between the other clinical parameters (age, stage, lymph node metastasis, thrombosis, and either 17q23-25 amplification, miR-21 overexpression, or PTEN protein loss). A significant correlation was observed between miR-21 overexpression and endometriosis. P-values were from two-sided tests and statistically significant when <0.05.
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