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Table 2 Univariate analysis (Mann–Whitney U test and Fisher exact test) for the development of grade 1–2 chronic GI complications

From: Dose-volume histogram predictors of chronic gastrointestinal complications after radical hysterectomy and postoperative intensity modulated radiotherapy for early-stage cervical cancer

 

Grade 0

Grade 1-2

 

Variable

No.

No.

P value

Age (y)

   

  ≤48

31

17

0.815

  >48

25

11

 

T-stage

   

  T1

42

21

1.000

  T2

14

7

 

N-stage

   

  N0

50

23

0.494

  N1

6

5

 

Histology

   

  SCC

53

27

1.000

  Others

3

1

 

Smoking

   

  None

51

28

0.164

  Yes

5

0

 

Diabetes

   

  None

52

25

0.681

  Yes

4

3

 

BMI (kg/m2)

   

  ≤25

29

16

0.817

  >25

27

12

 

Body position

   

  Prone

56

22

0.001

  Supine

0

6

 

RT total dose

   

  50.4 Gy

54

21

0.005

  >50.4 Gy

2

7

 

Concurrent chemotherapy

   

  None

34

9

0.020

  Yes

22

19

 

Chemotherapy regimens

   

  Cisplatin

7

5

0.703

  Docetaxel

15

14

 
  1. Abbreviations: GI = gastrointestinal; SCC = squamous cell carcinoma; BMI = body mass index; RT = radiation therapy.