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Table 3 Reproductive characteristics of Saudi breast cancer cases and controls

From: Obesity is a significant risk factor for breast cancer in Arab women

Parameter

Cases number (%)

Controls number (%)

OR 95% confidence intervals

P-values

Menopausal Status

   

< 0.0001

  Pre-menopause

264 (49.7)

484 (76.5)

1

  Postmenopausal

267 (50.3)

149 (23.5)

3.29 (2.56 – 4.22)

Age at menarche (years)

   

0.0767

  < 13

379 (70.9)

422 (66.1)

1

  ≥ 13

155 (29.1)

216 (33.9)

0.80 (0.62 – 1.03)

Breastfeeding

   

0.8739

  No

38 (8.0)

38 (8.0)

1

  Yes

440 (92.1)

457 (92.0)

0.96 (0.60 – 1.54)

Use of hormonal replacement therapy

   

< 0.0001

  No

191 (35.9)

329 (52.3)

1

  Yes

341 (64.1)

300 (47.7)

1.96 (1.55 – 2.48)

Age at menopause (years)

   

0.0001

  < 45

67 (30.0)

7 (8.0)

1

  ≥ 45

156 (70.0)

81 (92)

0.20 (0.09 – 0.46)

  1. Median values were used as cutoff point for age at menopause and age at menarche.
  2. Abbreviation: OR odds ratio.