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Table 4 Univariate Cox regression analysis for disease free survival and overall survival

From: Comparison of concurrent chemoradiotherapy versus neoadjuvant chemotherapy followed by radiation in patients with advanced nasopharyngeal carcinoma in endemic area: experience of 128 consecutive cases with 5 year follow-up

 

DFS

OS

 

Event

HR

95% CI

P-value

Event

HR

95% CI

P-value

Gender

        

 Male (n = 101)

41

1.00

  

33

1.00

  

 Female (n = 27)

8

0.69

0.32-1.47

0.33

3

0.35

0.11-1.14

0.08

WHO Classification

        

 Type I (n = 6)

3

1.00

  

1

1.00

  

 Type II (n = 43)

17

0.63

0.18-2.14

0.46

12

1.59

0.21-12.22

0.66

 Type III (n = 79)

29

0.61

0.19-2.02

0.42

23

1.68

0.23-12.47

0.61

cT

        

 T1-2 (n = 75)

21

1.00

  

13

1.00

  

 T3-4 (n = 53)

28

2.19

1.24-3.85

0.007

23

2.9

1.47-5.73

0.002

cN

        

 N0-1 (n = 34)

11

1.00

  

10

1.00

  

 N2-3 (n = 94)

38

1.38

0.70-2.70

0.35

26

1.06

0.49-2.13

0.95

Stage

        

 IIB/III (n = 83)

23

1.00

  

15

1.00

  

 IVA/IVB (n = 45)

26

2.70

1.54-4.74

0.0006

21

3.00

1.54-5.83

0.001

Treatment

        

 CCRT group (n = 90)

31

1.00

  

25

1.00

  

 NACT group (n = 38)

18

1.38

0.77-2.46

0.28

11

1.04

0.51-2.12

0.91

  1. DFS, disease free survival; OS, overall survival; HR, hazard ratio; CI, confidence interval.