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Figure 1 | BMC Cancer

Figure 1

From: FTY720 inhibits proliferation and epithelial-mesenchymal transition in cholangiocarcinoma by inactivating STAT3 signaling

Figure 1

FTY720 is cytotoxic to CC cells in a dose- and time-dependent manner. (A) MTT assay showing percentage of viable CC cells treated with 0, 5, 10, 15 and 20 μmol/L of FTY720 for 24 h. Data are presented as mean ± SD from three independent experiments. (B) CC cells were treated with FTY720 or vehicle for 72 hr, and proliferation measured using MTT assays. (C) Flow cytometry results of annexin V-PI stained CC cells after exposure to FTY720 (0 or 10 μmol/L) for 24 h. An increase in apoptotic cells following treatment with FTY720 is shown. Data are presented as the mean ± SD from three independent experiments. (D) A representative example of apoptosis of QBC939 cells treated with 10 μmol/L of FTY720 for 24 h.

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