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Table 5 Correlations between RNA expression of CXCL1 and gene expression of TGF-β signaling components

From: Elevated CXCL1 expression in breast cancer stroma predicts poor prognosis and is inversely associated with expression of TGF-β signaling proteins

Signaling component

r

95% CI

p-value

TGFB1

0.19

-0.09 to 0.45

0.18

TGFBR2

0.12

-0.16 to 0.39

0.12

SMAD2

0.33

0.06 to 0.57

0.01

SMAD3

0.11

-0.17 to 0.38

0.42

  1. Association between CXCL1 protein expression and expression of TGF-β signaling components was determined using Spearman Correlation analysis of IDC stroma and normal adjacent stroma.
  2. Significance determined by p<0.05. r= correlation coefficient.