Signaling component | r | 95% CI |
p-value |
---|
TGFB1
| 0.19 | -0.09 to 0.45 | 0.18 |
TGFBR2
| 0.12 | -0.16 to 0.39 | 0.12 |
SMAD2
| 0.33 | 0.06 to 0.57 | 0.01 |
SMAD3
| 0.11 | -0.17 to 0.38 | 0.42 |
- Association between CXCL1 protein expression and expression of TGF-β signaling components was determined using Spearman Correlation analysis of IDC stroma and normal adjacent stroma.
- Significance determined by p<0.05. r= correlation coefficient.