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Table 5 Correlations between RNA expression of CXCL1 and gene expression of TGF-β signaling components

From: Elevated CXCL1 expression in breast cancer stroma predicts poor prognosis and is inversely associated with expression of TGF-β signaling proteins

Signaling component r 95% CI p-value
TGFB1 0.19 -0.09 to 0.45 0.18
TGFBR2 0.12 -0.16 to 0.39 0.12
SMAD2 0.33 0.06 to 0.57 0.01
SMAD3 0.11 -0.17 to 0.38 0.42
  1. Association between CXCL1 protein expression and expression of TGF-β signaling components was determined using Spearman Correlation analysis of IDC stroma and normal adjacent stroma.
  2. Significance determined by p<0.05. r= correlation coefficient.
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