Figure 3

Increased CXCL1 RNA expression in breast cancer stroma is associated with poor prognosis. CXCL1 RNA expression values were obtained from the Finak microarray database, and analyzed for the following. A. The percentage of patients negative or positive for CXCL1 expression exhibiting tumor recurrence over time. The fractions below the graph depict recurrence-free patients over the total number of CXL1 negative or CXCL1 positive patients. B. Associations with overall tumor recurrence after 5 years. C. Associations with decreased survival after 5 years. Statistical analysis was performed using the Log-rank Test (A) or Wilcoxon Two-Sample Test (B and C). Mean ± SD. Statistical significance was determined by p <0.05. *p ≤0.001, ***p≥0.05.