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Table 2 Correlation between FAK expression and clinicopathological characteristics in primary tumors

From: High focal adhesion kinase expression in breast carcinoma is associated with lymphovascular invasion and triple-negative phenotype

Characteristic FAK ≤ 4 low FAK > 4 high Total number P-value
Number of cases 143 (73%) 53 (27%) 196  
Age (median) 57 51 56 0.033
Positive Lymph nodes (median) 3.0 5.0 4.0 0.062
Histological grade     
Grade I (well differentiated) 7 (5.2%)   7 0.143
Grade II (moderately differentiated) 23 (17.0%) 13 (24.5%) 36  
Grade III (poorly differentiated) 105 (77.8%) 40 (75.5%) 145  
Stage     
Stage IIA 48 (33.8%) 10 (18.9%) 58 0.124
Stage IIB 52 (36.6%) 23 (43.4%) 75  
Stage IIIA 12 (8.5%) 11 (20.8%) 23  
Stage IIIB 20 (14.1%) 6 (11.3%) 26  
Stage IIIC 3 (2.1%) 1 (1.9%) 4  
Stage IV 7 (4.9%) 2 (3.8%) 9  
Estrogen receptor (ER)     
Positive 115 (81.6%) 40 (75.5%) 155 0.346
Negative 26 (18.4%) 13 (24.5%) 39  
Progesterone receptor (PR)     
Positive 86 (61.0%) 26 (49.1%) 112 0.134
Negative 111 (79.3%) 41 (77.4%) 152  
HER-2     
Positive 29 (20.7%) 12 (22.6%) 41 0.770
Negative 111 (79.3%) 41 (77.4%) 152  
Triple negative status     
No 126 (90.6%) 42 (79.2%) 168 0.033
Lymphovascular invasion (LVI)     
No 75 (56.8%) 16 (30.8%) 91 0.001
Yes 57 (43.2%) 36 (54.4%) 93  
  1. The statistical significant correlation is marked by bold font.