Table 2 Common areas of loss, gain, deletion and amplification identified by aCGH in MDA-MB-231 PACR, ZR75-1 PACR and ZR75-1 DOCR at the two resistance levels 25nM and 50nM when compared to the native cell line
Cell line | Extending loss | Extending gain | Deletion | Amplification |
|---|---|---|---|---|
231 PACR | 1p36.13-q44 | 2p25.3-23.3 | 6p21.1 | 6p21.1 |
6p25.3-q12 | 3p24.3-q13.3 | 2q13 | 1q32.3 | |
8p | 4p16.1-q12 | 15q11,2 | 4q21.21-21.22 | |
10p | 5q14.3-q31.1 | 16 q11.2 | 8p12, 8p11.21 | |
19q | 8q21.13-24.3 | 11q13.2 | ||
X Chr. | 11q15.1-q25 | 12q14.1 | ||
centromeric 12 | 12q14.2 | |||
centromeric 14 | 12q15 | |||
15q11.2 | ||||
15q22.2-q22.3 | ||||
ZR75 PACR | 1q | None | None | None |
3p | ||||
7q | ||||
12p | ||||
15p | ||||
16q | ||||
ZR75 DOCR | 7q | None | None | None |
12p | ||||
16q |