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Table 2 EORTC QLQ-C30 functioning domains and time point of questionnaire completion (54 patients, 561 QOL assessments)

From: Assessing quality of life on the day of chemotherapy administration underestimates patients’ true symptom burden

EORTC QLQ-C30

At the hospital

At home (1 week later)

At home (2 weeks later)

Time point (main effect) F/p values

Estimated mean (95% CI)

 

Physical Functioning

81.4 1w (76.9-86.0)

74.8 Ho, 2w (70.2-79.4)

78.8 1w(74.1-83.6)

F = 13.32; p < 0.001

Social Functioning

72.3 1w, 2w(66.5-78.0)

67.1 Ho (61.3-72.9)

68.5 Ho(62.5-74.6)

F = 6.22; p = 0.002

Role Functioning

64.1 1w(58.2-70.0)

57.0 Ho, 2w (51.1-63.0)

62.2 1w(55.9-68.4)

F = 11.16; p < 0.001

Emotional Functioning

71.9 1w(67.2-72.6)

67.9 Ho, 2w(63.1-72.6)

70.8 1w(65.9-75.7)

F = 6.66; p = 0.001

Cognitive Functioning

89.6 1w(85.6-96.5)

86.4 Ho, 2w(82.4-90.3)

89.8 1w(85.6-93.9)

F = 6.91; p = 0.001

Global QOL

66.5 1w, 2w(62.6-70.5)

61.0 Ho (57.0-65.0)

62.5 Ho(58.3-66.7)

F = 12.1; p < 0.001

  1. superscript numbers indicate significance (p < 0.05) of post-hoc group comparisons (LSD-test).
  2. score differences to the hospital-based assessment exceeding 5 points are given in bold letters.