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Figure 4 | BMC Cancer

Figure 4

From: Immunohistochemical molecular phenotypes of gastric cancer based on SOX2 and CDX2 predict patient outcome

Figure 4

Gastric cancer cases with SOX2 protein expression (A and C) can present with or without SOX2 amplification (B and D, respectively) determined by FISH. Green labeled probes target SOX2, whereas red labeled probes target the 3p arm. Nuclei are stained with DAPI (blue). (E) Sixty-two gDNA gastric cancer samples were assessed for SOX2 copy number status and compared to normal gastric mucosa (calibrator). (F) SOX2 copy number was significantly associated with protein expression, determined by IHC (p < 0.05).

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