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Table 2 Frequency of expression of the metabolic markers along progression to malignancy in cervical samples

From: Lactate transporters and vascular factors in HPV-induced squamous cell carcinoma of the uterine cervix

 

MCT1

MCT4

CD147

GLUT1

CAIX

 

n

Positive (%)

p

n

Positive (%)

P

n

Positive (%)

p

n

Positive (%)

p

n

Positive (%)

p

   

0.252

  

0.005

  

0.071

  

0.025

  

0.004

Cervicitis

28

6 (21.4)

 

27

6 (22.2)

 

24

0 (0.0)

 

24

12 (50.0)

 

26

11 (42.3)

 

LSIL

33

9 (27.3)

 

30

8 (26.7)

 

34

2 (5.9)

 

34

29 (85.3)

 

34

4 (11.8)

 

HSIL

28

9 (32.1)

 

28

6 (21.4)

 

29

2 (6.9)

 

29

19 (65.5)

 

29

8 (27.6)

 

SCC

34

15 (44.1)

 

33

19 (57.6)

 

32

6 (18.8)

 

37

28 (75.7)

 

33

17 (51.5)

 
  1. Note: the number of lesion samples analysed for each marker varies due to loss of material during IHC procedure or lack of representativity of the lesion in the sample.