Table 3 Effect of Verbascoside on expression levels of apoptosis-related proteins in CRC xenograft tumors
From: Verbascoside promotes apoptosis by regulating HIPK2–p53 signaling in human colorectal cancer
Groups | n | Relative protein expression level | |||
|---|---|---|---|---|---|
HIPK2 | P53 | Bax | Bcl-2 | ||
Control | 6 | 3.23 ± 0.61 | 11.70 ± 2.08 | 9.82 ± 0.55 | 17.43 ± 1.50 |
20 mg/kg VB | 6 | 4.83 ± 0.62 | 14.59 ± 0.90 | 14.41 ± 0.38 | 14.08 ± 1.04 |
40 mg/kg VB | 6 | 8.46 ± 0.99 | 17.60 ± 1.40 | 15.84 ± 0.54 | 11.93 ± 0.93 |
80 mg/kg VB | 6 | 11.90 ± 1.21 | 23.10 ± 2.10 | 26.28 ± 0.55 | 7.48 ± 0.86 |
1 mg/kg 5-FU | 6 | 13.50 ± 0.94 | 22.44 ± 2.05 | 26.34 ± 2.33 | 5.46 ± 0.67 |