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Table 2 Relationship between clinicopathological parameters and HIPK2 expression in human CRC

From: Verbascoside promotes apoptosis by regulating HIPK2–p53 signaling in human colorectal cancer

Variable N Nat different HIPK2 expression levels χ2 P
Low expression High expression
+ ++ +++
Sex        
  Male 47 23 13 7 4 0.31 >0.05
  Female 53 26 12 12 3
Age (years)        
  ≤60 29 11 9 7 2 0.88 >0.05
  >60 71 38 16 12 5
Maximum diameter of tumor        
  ≤5 58 30 16 8 4 2.02 >0.05
  >5 42 19 9 11 3
Degree of differentiation        
  Well differentiated 12 7 2 2 1 6.44 <0.05
  Moderately differentiated 67 33 16 12 6
  Poorly differentiated 5 1 4 0 0
Depth of invasion        
  Not invading serosa 42 28 7 5 2 4.71 >0.05
  In serosa 25 6 9 9 1
  Outside serosa 33 15 9 5 4
Duke stage        
  Stages A and B 72 35 19 15 3 0.13 >0.05
  Stages C and D 28 14 6 4 4
Lymph node status        
  Metastasis 65 32 18 12 3 0.82 >0.05
  No metastasis 35 17 7 7 4
TNM stage        
  Stages I and II 57 31 14 11 1 1.69 >0.05
  Stages III and IV 43 18 11 8 6