Figure 4From: In vivo dual targeting of the oncogenic Ether-à-go-go-1 potassium channel by calcitriol and astemizole results in enhanced antineoplastic effects in breast tumors The combined treatment with calcitriol and astemizole downregulated EAG1 gene expression in the tumoral tissue. The gene expression of tumoral EAG1 was assessed by RT-qPCR and normalized against the corresponding housekeeping gene. Values for controls were arbitrarily set to one. Black bars = MBCDF; white bars = T-47D. *P < 0.05 vs. control in each group; n ≥ 15. Results are expressed as the mean ± standard error.Back to article page