Table 2 Univariate and multivariate analysis of clinicopathological parameters influencing prognosis

Gender

Male

0.25

0.064

Female

Age

<50 years

0.079

0.078

≥50 years

HBs-Ag

Negative

0.412

0.978

Positive

AFP (ng/ ml)

<200

0.021

0.209

≥200

Edmonson grading

I-II

0.277

0.788

III-IV

Tumor size

<5 cm

< 0.001

< 0.001

1.991 (1.383-2.867)

0.001

< 0.001

1.919 (1.291-2.582)

≥5 cm

Surgical margin

<1 cm

0.001

0.002

≥1 cm

Liver cirrhosis

Absent

0.505

0.91

Present

Monocyte count (/mm ³ )

<545

< 0.001

0.01

1.393 (1.083-1.793)

< 0.001

0.002

1.578 (1.187-2.097)

≥545

PVTT

Absent

0.545

0.911

Present

Capsulation

Capsulated

< 0.001

< 0.001

1.597 (1.231-2.071)

0.002

< 0.001

1.793 (1.371-2.345)

Non-caspulated

Tumor number

Single

< 0.001

0.005

1.513 (1.134-2.019)

< 0.001

< 0.001

1.771 (1.312-2.392)

Multiple

Macrovascular invasion

Absent

0.012

0.086

Present