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Table 2 Univariate associations between explanatory variables and breast cancer in the derivation cohort

From: Development and validation of a clinical prediction rule to identify suspected breast cancer: a prospective cohort study

Explanatory variable Unadjusted odds ratio 95% confidence interval (CI) P-value
Age 1.07 1.07-1.08 <0.01
Abscess 0.53 0.20-1.44 0.22
Inflammation 0.53 0.20-1.44 0.22
Family history 0.99 0.91-1.07 0.71
Lump 3.33 2.56-4.30 <0.01
Nipple changes 1.93 1.24-3.01 <0.01
Skin changes 1.73 0.69-4.35 0.24
Nipple discharge 1.19 0.67-2.11 0.55
Ulceration 1.73 0.69-4.35 0.24
Nodularity 2.18 0.28-17.26 0.46
  1. Note: Explanatory variables had to be considered of prior clinical importance (nipple discharge may indicate pathologic nipple discharge) or be associated with a threshold p-value of ≤ 0.15.