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Table 2 Univariate associations between explanatory variables and breast cancer in the derivation cohort

From: Development and validation of a clinical prediction rule to identify suspected breast cancer: a prospective cohort study

Explanatory variable

Unadjusted odds ratio

95% confidence interval (CI)

P-value

Age

1.07

1.07-1.08

<0.01

Abscess

0.53

0.20-1.44

0.22

Inflammation

0.53

0.20-1.44

0.22

Family history

0.99

0.91-1.07

0.71

Lump

3.33

2.56-4.30

<0.01

Nipple changes

1.93

1.24-3.01

<0.01

Skin changes

1.73

0.69-4.35

0.24

Nipple discharge

1.19

0.67-2.11

0.55

Ulceration

1.73

0.69-4.35

0.24

Nodularity

2.18

0.28-17.26

0.46

  1. Note: Explanatory variables had to be considered of prior clinical importance (nipple discharge may indicate pathologic nipple discharge) or be associated with a threshold p-value of ≤ 0.15.