Skip to main content

Table 1 Data on resection versus non-resection of the primary tumour in metastatic CRC patients

From: The CAIRO4 study: the role of surgery of the primary tumour with few or absent symptoms in patients with synchronous unresectable metastases of colorectal cancer – a randomized phase III study of the Dutch Colorectal Cancer Group (DCCG)

Study Years of study Number of patients Median survival time (in months) p-value
   Resection Non-resection Resection Non-resection  
Liu[20] 1986-1991 57 5 11 2 n.a.
Ruo[24] 1996-1999 127 103 16 9 <0.001
Kaufman[25] 1998-2003 115 69 22 3 <0.0001
Scoggins[13] 1985-1997 66 23 14.5 16.6 0.59
Tebbutt[26] 1990-1999 280 82 14 8.2 0.08
Michel[27] 1996-1999 31 23 21 14 0.718
Benoist[16] 1997-2002 32 27 23 22 n.a.
Evans[28] 1999-2006 45 57 11 2 < 0.0001
Poultsides[15] 2000-2006 - 178 - 13  
Venderbosch[23] 2003-2004 258 141 16.7 11.4 < 0.0001
2005-2006 289 159 20.7 13.4 <0.0001
  1. n.a. = not applicable.