Heat maps of PTEN hybridizations by tissue microarrays (TMA) for CSI, CSII and CSIII patients. Each row represents the staining level for the proteins in non-metastatic (NM) or metastatic (M) patients. Each column shows PTEN hybridizations performed in duplicates, analyzed by two different pathologists (showing four results). The color key scale represented by bright red (level 2) indicates score 3, weak red (level 1) for score 2, black (level 0) for score 1 and green (level -2) for no staining (score = 0). Missing data is represented in white.