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Table 1 The percentages of surface receptor- and cytotoxic granule-positive NK-92 cells co-cultured with SW1990 compared to those cultured alone

From: Elevation of MMP-9 and IDO induced by pancreatic cancer cells mediates natural killer cell dysfunction

  NK-92 + Medium (%) NK92 + SW1990 (%) P-value
NKG2D 94.72 ± 0.49 23.73 ± 2.05 <0.001
NKp30 27.36 ± 0.08 3.81 ± 0.17 <0.001
NKp44 24.33 ± 2.07 0.93 ± 0.48 <0.01
NKp46 11.76 ± 1.14 1.73 ± 1.03 <0.01
DNAM-1 51.35 ± 2.06 2.63 ± 1.13 <0.001
KIR3DL1 2.06 ± 0.65 1.78 ± 1.19 Ns
KIR2DL1/DS1 1.79 ± 0.96 2.50 ± 0.85 Ns
NKp80 92.67 ± 2.74 91.61 ± 2.85 Ns
Perforin 95.68 ± 0.52 40.93 ± 0.49 <0.001
Granzyme B 95.81 ± 1.96 86.24 ± 3.01 <0.01
  1. All experiments were repeated three times. All data were expressed as mean ± SD. Independent t-tests were used for statistical analysis through SPSS 19.0 software. P < 0.01 is considered significant; P < 0.001 is considered highly significant.