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Table 1 Patient demographic and disease characteristics

From: Dose-intense capecitabine, oxaliplatin and bevacizumab as first line treatment for metastatic, unresectable colorectal cancer: a multi-centre phase II study

 

Total

C1750 mg/m2

C1500 mg/m2

 

n = 49

n = 19

n = 30

Age at registration, median (IQ range)

63 (55, 67)

64 (52, 68)

62 (55, 65)

Gender, n (%)

   

Female

31 (63.3)

11 (57.9)

20 (66.7)

Male

18 (36.7)

8 (42.1)

10 (33.3)

Ethnicity, n (%)

   

European

47 (96.0)

18 (94.7)

29 (96.7)

Maori

1 (2.0)

1 (5.3)

0 (0.0)

Other

1 (2.0)

0 (0.0)

1 (3.3)

Histology, n (%)

   

Adenocarcinoma - NOS

20 (40.8)

7 (36.8)

13 (43.3)

Adenocarcinoma - poorly differentiated

4 (8.2)

2 (10.5)

2 (6.7)

Adenocarcinoma - moderately differentiated

17 (34.7)

9 (47.4)

8 (26.7)

Adenocarcinoma - well differentiated

1 (2.0)

1 (5.3)

0 (0.0)

Mucinious

7 (14.3)

0 (0.0)

7 (23.3)

Disease Status, n (%)

   

Distant metastases only

41 (83.7)

17 (89.5)

24 (80.0)

Local recurrence

5 (10.2)

2 (10.5)

3 (10.0)

Distant metastases and local recurrence

3 (6.1)

0 (0.0)

3 (10.0)

Prior Anticancer Treatment, n (%)

   

Prior Adjuvant Chemotherapy

11 (22.4)

5 (26.3)

6 (20.0)

Radiotherapy

8 (16.3)

3 (15.8)

5 (16.7)

Surgery

44 (89.8)

17 (89.5)

27 (90.0)

WHO Performance Status, n (%)

   

0

42 (85.7)

18 (94.7)

24 (80.0)

1

7 (14.3)

1 (5.3)

6 (20.0)