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Table 1 IC 50 values (μM) for 1, 2, and cisplatin on MCF-7, MDA-MB-231 and HCC1937 cells after 24 h of treatment (data reflect the mean and ± SD of results from three separate experiments, each performed in triplicate)

From: Cellular responses of BRCA1-defective and triple-negative breast cancer cells and in vitro BRCA1 interactions induced by metallo-intercalator ruthenium(II) complexes containing chloro-substituted phenylazopyridine

Metal complexes IC50(μM)
MCF-7 MDA-MB-231 HCC1937
Cisplatin 42.2 ± 8 *,** 128.2 ± 7 *,** 23.4 ± 7 *,**
1 10.7 ± 0.6 *,** 14.1 ± 0.5 *,** 9.9 ± 0.2 *,**
2 8.2 ± 0.1 *,** 13.2 ± 0.3 *,** 1.8 ± 0.1 *,**
  1. Statistical significance differences are indicated by *p < 0.01, compared the IC50 values of the same complex on cell lines, and **p < 0.01, compared the IC50 values of the complexes on each cell line.