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Figure 5 | BMC Cancer

Figure 5

From: Cellular responses of BRCA1-defective and triple-negative breast cancer cells and in vitro BRCA1 interactions induced by metallo-intercalator ruthenium(II) complexes containing chloro-substituted phenylazopyridine

Figure 5

Flow cytometric analysis of the cell cycle phase distribution in response to 1 and 2. MCF-7 (A), MDA-MB-231 (B), and HCC1937 (C) cells were treated with appropriate IC50 concentrations of 1 and 2 for 24 h, and the DNA content was then analyzed by propidium iodide (PI) staining. The results were expressed as a histogram display of their DNA content (x-axis: PI fluorescence) versus counts (y-axis). The phases of the cell cycle from the left to the right were sub-G1-phase, G0/G1-phase, S-phase, and G2/M-phase, respectively.

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