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Figure 3 | BMC Cancer

Figure 3

From: Cellular responses of BRCA1-defective and triple-negative breast cancer cells and in vitro BRCA1 interactions induced by metallo-intercalator ruthenium(II) complexes containing chloro-substituted phenylazopyridine

Figure 3

Real-time monitoring of the ruthenium(II) polypyridyl complexes, 1 and 2, effects on human breast cancer cells using the xCEEL igence system. Cells [MCF-7 (A), MDA-MB-231 (B), and HCC1937 (C)] were seeded onto the E-plate and allowed to grow prior to the introduction of the metal complexes at various concentrations. After addition of the metal complexes, cells were allowed to grow for 24 h in the presence of 1 or 2. The complexes were then removed and fresh medium was added. Cells were then allowed to grow for 24 h to assess the recovery of cell proliferation after ruthenium treatments. The cell index (CI) was recorded every 15 min. Each concentration was performed in triplicate.

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BMC Cancer

ISSN: 1471-2407

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