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Table 3 Sensitivity analysis of mortality using multivariable Cox regression techniques

From: Survival in overweight patients with advanced pancreatic carcinoma: a multicentre cohort study

  Univariable Multivariable
Variable HR 95% CI P-value HR 95% CI P-value
BMI 1.30 1.13 - 1.48 <0.001 1.28 1.10. – 1.50 0.001
(in steps of 5)
Age (continuously) 1.00 0.99 - 1.01 0.695 1.00 0.99 - 1.01 0.405
Performance status 0.73 0.60 - 0.94 0.015 0.70 0.54 - 0.91 0.009
(ECOG < 2 versus ECOG ≥ 2)
Diabetes 0.87 0.69 - 1.09 0.234 0.78 0.61 - 1.01 0.064
(yes versus no)
Stage 0.98 0.74 - 1.30 0.912 1.10 0.80 - 1.47 0.601
(stage III versus stage IV)
Sex 1.35 1.10 - 1.66 0.004 1.30 1.04 -1.63 0.023
(male versus female)
CA 19-9 1.08 1.04 - 1.12 <0.001 1.06 1.02 - 1.11 0.006
(continuously on log scale)
  1. Only patients treated with gemcitabine-based first-line therapy were included (N = 407). Abbreviations: BMI body mass index, CI confidence interval, ECOG Eastern Cooperative Oncology Group, HR hazard ratio.