Table 3 Nuclear and cytoplasmic Ep-ICD expression in invasive ductal carcinoma (IDC) and correlation with clinicopathological parameters

IDC cases

75

42

-

-

145

81

-

-

Age

< 59 years

88

39

44.3

74

84.1

≥ 59 years

92

36

39.1

0.480

0.80 (0.45–1.45)

71

77.2

0.241

0.64(0.30–1.36)

Tumor Size ^a

≤2 cm

81

35

43.2

69

85.2

> 2 cm

96

37

38.5

0.529

0.82 (0.45–1.50)

73

76.0

0.128

0.55(0.25–1.20)

T-stage

T ₁  + T ₂

171

71

41.5

138

80.7

T ₃  + T ₄

9

4

44.4

0.862

1.13 (0.30–4.34)

7

77.8

0.829

0.84(0.17–4.22)

Nodal Status

N _x+0

123

58

47.2

99

80.5

N _1–3

57

17

29.8

0.028

0.48 (0.24–0.98)

46

80.7

0.973

1.02(0.45–2.24)

Stage

I + II

159

68

42.8

130

81.8

III + IV

21

7

33.3

0.410

0.67 (0.26–1.74)

15

71.4

0.261

0.56(0.20–1.56)

Grade ^b

I + II

108

53

49.1

90

83.3

III

65

20

30.8

0.018

0.46 (0.24–0.89)

48

73.8

0.132

0.57(0.27–1.20)

Clinical Recurrence

No

155

50

32.3

121

78.1

Yes

25

25

100

<0.001

1.50 (1.28–1.76)

24

96.0

0.035

6.75(0.88–51.67)

ER/ PR status ^c

ER ⁺

136

62

45.6

112

82.4

ER ^-

33

12

36.4

0.338

1.47 (0.67–3.22)

25

75.8

0.386

1.49(0.60–3.71)

PR ⁺

103

49

47.6

88

85.4

PR ^-

64

25

39.1

0.282

1.42 (0.75–2.67)

48

75.0

0.092

1.96(0.89–4.30)

ER ⁺ PR ⁺

103

49

47.6

88

85.4

ER ^- PR ^-

33

12

36.4

0.260

1.59(0.70–3.56)

25

75.8

0.197

1.96(0.89–4.30)