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Table 3 The correlation of mRNA expression of Kiss-1R and clinical parameters

From: Implication of metastasis suppressor gene, Kiss-1 and its receptor Kiss-1R in colorectal cancer

Category   No. Median IQR p
T/Na     
  Normal 80 30 1-2406  
  Tumour 94 <0.000001 <0.000001 <0.0001c
Paired T/Na     
  Paired normal 68 23 0-522  
  Paired tumour 68 <0.000001 0-0.02 <0.0001c
Location     
  Left colon 22 <0.000001 <0.000001-0.01  
  Right colon 28 <0.000001 <0.000001-0.009 0.8791
  Transcolonb 2 0.00452 N/A  
  Rectum 22 <0.000001 <0.000001-0.13 0.447
Dukes classification     
  A 7 0.00015 <0.000001-0.00103  
  B 33 0.0004 <0.000001-0.0091 0.6616
  C 32 <0.000001 <0.000001-0.09 0.1431
Tumour stage     
  T1 2 1.06E-05 N/A  
  T2 10 0.00005 <0.000001-0.00171  
  T3 40 <0.000001 <0.000001-0.03  
  T4 18 <0.000001 <0.000001-0.02  
Lymph node involvement     
  Node 0d 39 0.0003 <0.000001-0.0071  
  Node 1d 16 <0.000001 <0.000001-0.02 0.3236
  Node 2d 15 0.01 <0.000001-1.76 0.335
TNM staging     
  I 9 0.00003 <0.000001-0.00033  
  II 30 0.0005 <0.000001-0.0105 0.1939
  III&IV 32 <0.000001 <0.000001-0.09 0.051
Clinical outcome     
  No invasion 50 <0.000001 <0.000001-0.008  
  Invasion 26 <0.000001 <0.000001-0.05 0.1907
  Disease free 35 0.00019 <0.000001-0.00523  
  Incidence 23 0.01 <0.000001-0.12 0.0207c
  No recurrence 58 <0.000001 <0.000001-0.013  
  Local recurrence 7 0.00653 <0.000001-0.02245 0.6923
  No metastasis 50 <0.000001 <0.000001-0.009  
  Metastasis 19 <0.000001 <0.000001-0.13 0.0765
  Alive 36 0.00028 <0.000001-0.00724  
  Death 22 <0.000001 <0.000001-0.13 0.0158c
  Non treat 42 0.0002 <0.000001-0.006  
  Chemradio 5 0.0796 0.012-0.1607 0.0115c
  1. aTumour (T), Normal (N). bTransverse colon. c p < 0.05. dNode 0 stands for no node involvement; Node 1 stands for 1 to 3 lymph nodes close to the bowel found to contain cancer cells; Node 2 stands for more than 3 lymph nodes found to contain cancer cells and further than 3cm away from the main tumor in the bowel or the presence of cancer cells in lymph nodes connected to the main blood vessels around the bowel.