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Table 4 Correlations between the DVH a -based parameters and acute grade ≥2 RP b in present study (n = 23)

From: Stereotactic body radiation therapy for post-pulmonary lobectomy isolated lung metastasis of thoracic tumor: survival and side effects

 

Grade ≥2 RIP (n = 8)

Grade 0–1 RIP (n = 15)

p value

mean ± SD

mean ± SD

Total Lungs

   

V5 (%)c

36.0 ± 6.0

35.0 ± 4.0

0.141

V10 (%)c

16.0 ± 4.0

14.0 ± 2.0

0.125

V20 (%)c

4.8 ± 2.0

4.4 ± 1.2

0.696

V30 (%)c

2.0 ± 1.0

2.0 ± 1.0

0.990

MLD (Gy) d

3.8 ± 1.6

3.7 ± 1.3

0.077

Contralateral lungs

   

V5 (%)

26.0 ± 7.0

25.0 ± 9.0

0.421

V10 (%)

18.0 ± 7.0

16.0 ± 9.0

0.277

V20 (%)

3.2 ± 1.1

2.4 ± 0.9

0.210

V30 (%)

1.6 ± 0.5

1.6 ± 0.6

0.992

MLD (Gy)

2.8 ± 0.6

2.6 ± 0.2

0.483

Ipsilateral lungs

   

V5 (%)

51.0 ± 9.1

44.0 ± 4.0

0.034

V10 (%)

22.0 ± 6.0

19.0 ± 4.0

0.273

V20 (%)

6.0 ± 2.8

5.2 ± 2.2

0.454

V30 (%)

2.6 ± 1.0

2.8 ± 1.1

0.824

MLD (Gy)

5.9 ± 1.3

5.7 ± 1.1

0.290

PTV volume (cm 3 )

59.0 ± 9.6

45.0 ± 9.9

0.039

  1. a: dose-volume histogram; b: radiation pneumonitis; c: the percentage of the lung volume that received more than 5, 10, 20 and 30 Gy irradiation dose, respectively; d: mean lung dose.