Table 4 Multivariable logistic regression analysis of the association between ethnicity and ALCAM expression in breast cancer
From: Enhanced down-regulation of ALCAM/CD166 in African-American Breast Cancer
| Â | Membranous ALCAM level n (%) | Â | Â | |
|---|---|---|---|---|
| Â | IRS 0-7 | IRS 8-12 | Odds ratio (95% CI) | P value |
Ethnicity | Â | Â | Â | Â |
AA | 37 (72.55) | 41 (33.61) | 4.28(1.64- 11.15) | 0.003 |
CAU | 14 (27.45) | 81 (66.39) | Reference | Â |
Age in years | Â | Â | Â | Â |
≤50 | 13 (25.49) | 39 (31.97) | 0.69 (0.24- 1.99) | 0.49 |
>50 | 38 (74.51) | 83 (68.03) | Reference | Â |
Histological grade | Â | Â | Â | Â |
Poor | 22 (50.00) | 19 (16.52) | 2.10(0.60- 7.34) | 0.25 |
Well-moderately | 22 (50.00) | 96 (83.48) | Reference | Â |
Tumor size | Â | Â | Â | Â |
Large (>2Â cm) | 17 (41.46) | 31 (28.18) | 0.62( 0.20-1.88) | 0.39 |
Small (≤2 cm) | 24 (58.54) | 79 (71.82) | Reference |  |
Lymph node | Â | Â | Â | Â |
Positive | 15 (40.54) | 33 (34.02) | 1.62( 0.58- 4.54) | 0.36 |
Negative | 22 (59.46) | 64 (65.98) | Reference | Â |
Basal-like (TN) | Â | Â | Â | Â |
Yes | 25 (51.02) | 10 (8.85) | 5.59(1.46- 21.50) | 0.01 |
No | 24 (48.98) | 103 (91.15) | Reference | Â |