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Table 3 Membranous ALCAM expression and clinical and histological tumor characteristics of AA and CAU breast cancer

From: Enhanced down-regulation of ALCAM/CD166 in African-American Breast Cancer

  Membranous ALCAM (n,%) in Caucasian Membranous ALCAM (n,%) in African American
  IRS 0-7 IRS 8-12 p value IRS 0-7 IRS 8-12 p value
Age in years    0.41    0.65
≤50 3(3.1) 26(27.4)   10(12.8) 13(16.7)  
>50 11(11.6) 55(57.9)   27(34.6) 28(35.9)  
Histological Type    0.38    0.93
IDC 10(11.4) 64(72.7)   36(46.2) 40(51.3)  
ILC 0(0) 7(8)   1(1.3) 1(1.3)  
IDC&ILC 1(1.1) 6(6.8)   0(0) 0(0)  
Histological Grade    0.02*    0.04*
G1 3(3.3) 26(28.9)   5(7.2) 11(15.9)  
G2 3(3.3) 41(45.6)   11(15.9) 18(26.1)  
G3 6(6.7) 11(12.2)   16(23.2) 8(11.6)  
Tumor size    0.71    0.82
T1 9(10) 60(66.7)   15(24.6) 19(31.1)  
T2 3(3.3) 12(13.3)   9(14.8) 11(18.0)  
T3-T4 1(1.1) 5(5.5)   4(6.6) 3(4.9)  
Lymph node status    0.95    0.44
Negative 6(8.2) 42(57.5)   16(26.2) 22(36.1)  
Positive 3(4.1) 22(30.1)   12(19.7) 11(18)  
ER status    0.0015*    0.0004*
Negative 7(8.2) 8(9.4)   21(28) 9(12)  
Positive 6(7.1) 64(75.3)   13(17.3) 32(42.7)  
PR status    0.034*    0.002*
Negative 8(8.9) 20(23.5)   22(29.3) 12(16)  
Positive 5(5.9) 52(61.2)   12(16) 29(38.7)  
HER2-neu status    0.14    0.096
Negative 12(14) 55(63.9)   31(41.9) 34(45.9)  
Positive 1(1.2) 18(20.9)   2(2.7) 7(9.5)  
Triple Negative    0.0006*    0.0002*
Yes 6(7.1) 4(4.8)   19(25) 6(7.9)  
No 7(8.3) 67(79.8)   16(21.1) 35(46.1)  
  1. *Age-adjusted.