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Table 2 Characteristics of the SNPs

From: Factors modifying the risk for developing acute skin toxicity after whole-breast intensity modulated radiotherapy

Gene or gene regulator

rs number

MAF*

Nucleotide substitution

Genomic location

Amino acid substitution

Reference

LIG3

rs3744355

9.1

G > C

5′-flanking

-

[12, 13]

MLH1

rs1800734

22.6

G > A

5′-UTR

-

[14]

XRCC3

rs861539

39.0

C > T

Coding

Thr241Met

[15]

PHLDA3

rs3888929

30.3

G > A

Unknown

-

[16]

LCP2

rs4867592

19.1

C > A

Unknown

-

[16]

LTHA4

rs7970524

25.1

T > C

5′-flanking

-

[16]

NDUFB6

rs12003093

23.4

A > G

Unknown

-

[16]

VDR

rs4760658

36.6

A > G

Intronic

-

[16]

  1. *Minor allele frequency in Caucasian population.
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BMC Cancer

ISSN: 1471-2407

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