Table 2 Predictive variables for overall survival and recurrence-free survival of 216 patients with gastric cancer
From: ALDH1A1 overexpression is associated with the progression and prognosis in gastric cancer
Variables | No. of patients | OS rate (%) | P-value | RFS rate (%) | P-value | ||
|---|---|---|---|---|---|---|---|
3 y | 5 y | 3 y | 5 y | ||||
Gender | |||||||
Male | 140 | 46.9 | 39.6 | 41.5 | 35.4 | ||
Female | 76 | 54.0 | 43.1 | 0.308 | 44.4 | 41.2 | 0.381 |
Age (years) | |||||||
≤ 60 | 136 | 49.8 | 43.9 | 45.3 | 42.2 | ||
> 60 | 80 | 48.9 | 36.1 | 0.338 | 38.1 | 30.6 | 0.391 |
Size (cm) | |||||||
≤ 5.0 | 139 | 55.6 | 47.4 | 50.4 | 45.5 | ||
> 5.0 | 77 | 38.1 | 28.8 | 0.001 | 28.3 | 23.3 | < 0.001 |
Tumor site | |||||||
Upper | 86 | 45.9 | 33.8 | 34.6 | 28.6 | ||
Middle/Lower | 130 | 51.8 | 45.7 | 0.074 | 47.8 | 43.7 | 0.047 |
Differentiation | |||||||
Well/Moderate | 96 | 47.8 | 39.7 | 41.2 | 34.6 | ||
Poor | 120 | 50.7 | 41.6 | 0.673 | 43.6 | 40.1 | 0.822 |
Depth of invasion | |||||||
T1/T2 | 81 | 71.4 | 66.5 | 70.2 | 65.3 | ||
T3/T4 | 135 | 36.2 | 25.5 | < 0.001 | 25.6 | 20.8 | < 0.001 |
Lymph node metastasis | |||||||
Negative | 59 | 83.5 | 79.2 | 82.0 | 77.5 | ||
Positive | 157 | 36.5 | 26.6 | < 0.001 | 27.5 | 22.6 | < 0.001 |
ALDH1A1 protein expression | |||||||
Negative | 108 | 69.3 | 57.1 | 60.5 | 54.8 | ||
Positive | 108 | 28.7 | 23.9 | < 0.001 | 23.7 | 19.2 | < 0.001 |