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Figure 7 | BMC Cancer

Figure 7

From: Btbd7 contributes to reduced E-cadherin expression and predicts poor prognosis in non-small cell lung cancer

Figure 7

Downregulation of Btbd7 expression in NCI-H1299 cells using Btbd7 siRNA significantly upregulates E-cadherin expression. (A) Western blotting study shows effective downregulation of Btbd7 using Btbd7 siRNA significantly upregulates E-cadherin expression and downregulates slug, MMP2 and MMP7 expression (p < 0.05). (B) Immunofluorescent staining shows that downregulation of Btbd7 in NCI-H1299 cells effectively restores E-cadherin expression in cell membrane (×400).

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